在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYOG Antibody

MYOG Antibody

  • 中文名稱：
    MYOG兔多克隆抗體
  • 貨號：
    CSB-PA003347
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of A549 cells using Myogenin Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MYOG
  • 別名：
    bHLHc3 antibody; cb553 antibody; Class C basic helix-loop-helix protein 3 antibody; MYF 4 antibody; Myf-4 antibody; MYF4 antibody; MYOG antibody; MYOG_HUMAN antibody; Myogenic factor 4 antibody; Myogenic factor 4 myogenin antibody; Myogenin antibody; Myogenin myogenin factor 4 antibody; OTTHUMP00000039094 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Myogenin.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1. Together with MYF5 and MYOD1, co-occupies muscle-specific gene promoter core regions during myogenesis. Cooperates also with myocyte-specific enhancer factor MEF2D and BRG1-dependent recruitment of SWI/SNF chromatin-remodeling enzymes to alter chromatin structure at myogenic late gene promoters. Facilitates cell cycle exit during terminal muscle differentiation through the up-regulation of miR-20a expression, which in turn represses genes involved in cell cycle progression. Binds to the E-box containing (E1) promoter region of the miR-20a gene. Plays also a role in preventing reversal of muscle cell differentiation. Contributes to the atrophy-related gene expression in adult denervated muscles. Induces fibroblasts to differentiate into myoblasts.
  • 基因功能參考文獻：
    1. Findings indicate a interplay between A-kinase anchoring protein 6 (AKAP6) and myogenin. PMID: 26563778
    2. results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle PMID: 25044114
    3. Sustained GSK3beta activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma. PMID: 24577092
    4. Our study illustrates that focal myogenin immunoreactivity occurs uncommonly in fibroepithelial polyps of the lower female genital tract. PMID: 23944986
    5. Data indicate that muscle MYOG mRNA expression doubled, whereas MSTN protein expression decreased following immobilization. PMID: 24215591
    6. the FACT complex promotes myogenin-dependent transcription PMID: 23364797
    7. Human muscle samples were analysed at different time-points post-denervation to evaluate changes in myogenin expression and their relationship with skeletal muscle atrophy. PMID: 21672341
    8. After 2 years of denervation, expression of myogenin protein in myonuclei was decreased, but after 3 years of denervation, no expression of myogenin protein in myonuclei was found in denervated posterior cricoarytenoid muscles. PMID: 19961777
    9. The physical interaction of CARM1 and PCAF is likely pivotal for the activation of PCAF in the downstream of CARM1 pathway for inducing myogenin under Tetradecanoylphorbol Acetate -induced differentiation. PMID: 20213728
    10. study showed that a rapid rearrangement of myogenin expression occurs in exercised human skeletal muscles in response to a single bout of exercise PMID: 14997318
    11. myogenin and myocyte enhancer factor-2 expression are triggered by membrane hyperpolarization during human myoblast differentiation PMID: 15084602
    12. induction of Id1 not only blocks transcriptional activity but also induces myogenin degradation by blocking formation of myogenin-E47 protein complexes. PMID: 15322112
    13. there is a functional link between dysferlin and myogenin in the differentiation of skeletal muscle PMID: 16608842
    14. MYOG is a positive diagnostic for biliary tract rhabdomyosarcoma. PMID: 17378682
    15. MYOG had positive staining in this melanotic neuroectodermal tumor. PMID: 17378694
    16. Both PCAF and BRG1 are also involved in the activation of the myogenin gene in rhabdomyosarcoma PMID: 17468105
    17. transcription of Cugbp1 gene in muscle is regulated by myogenin and E proteins PMID: 17531403
    18. Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma. PMID: 18708938
    19. PAX3 mRNA is an Staufen 1-mediated mRNA decay target whose decay promotes myogenesis whereas myogenin mRNA is a classical nonsense-mediated mRNA decay target encoding a protein required for myogenesis PMID: 19095803
    20. Underexpression of myogenin is associated with liver metastases in rhabdomyosarcoma. PMID: 19372547
    21. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. PMID: 19470832

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 7612

    OMIM: 159980

    KEGG: hsa:4656

    STRING: 9606.ENSP00000241651

    UniGene: Hs.2830



主站蜘蛛池模板： 137裸交肉体摄影| 亚洲国产无线乱码在线观看| 曰韩少妇内射免费播放| 日本牲交大片无遮挡| 国产综合18久久久久久| 一区二区免费高清观看国产丝瓜| 无码人妻精品一区二区蜜桃百度 | 日韩人妻无码精品二专区| 亚洲精品久久久久久中文| 国产美女极度色诱视频www| 在线 无码 中文字幕 强 乱| 中字幕久久久人妻熟女天美传媒 | 亚洲成a人无码| 欧美老妇大p毛茸茸 | 久久天天躁夜夜躁狠狠躁2014| 东京热无码国产精品| 久久香蕉国产线看观看精品yw| 国产欧美精品一区二区三区-老狼| 国产成人av国语在线观看| 国产精品成人亚洲777| 日日大香人伊一本线久| 国产成人av一区二区三区在线观看| 人人做人人爽人人爱| 免费全部高h视频无码| 亚洲va中文字幕无码一二三区| 午夜三级a三级三点窝| 美女扒开尿口让男人桶| 亚洲欧洲自拍拍偷综合| 亚洲精品中国国产嫩草影院美女| 最近中文字幕在线中文视频| 久久亚洲精品高潮综合色a片| 人妻无码手机在线中文| 亚洲精品中文字幕无码蜜桃| 色欲麻豆国产福利精品| 久久精品人人做人人爽老司机 | 久久久久精品无码一区二区三区 | 天天躁久久躁日日躁| 久久无码人妻一区二区三区午夜 | 亚洲国产精品自产在线播放| 国产嫖妓风韵犹存对白| 老司机午夜精品视频资源|