在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYO1E Antibody

MYO1E Antibody

  • 中文名稱：
    MYO1E兔多克隆抗體
  • 貨號：
    CSB-PA015342GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MYO1E
  • 別名：
    FSGS6 antibody; HuncM-IC antibody; MYO1C antibody; Myo1e antibody; MYO1E variant protein antibody; MYO1E_HUMAN antibody; Myosin heavy chain myr 3 antibody; Myosin IC, formerly antibody; Myosin IE antibody; Myosin-Ic antibody; Myr 3 antibody; Myr3 antibody; MYR5 antibody; Unconventional myosin 1E antibody; Unconventional myosin Ie antibody; Unconventional myosin-Ie antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MYO1E
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
  • 基因功能參考文獻：
    1. our data suggests that MYO1E contributes to breast tumor malignancy and regulates the differentiation and proliferation state of breast tumor cells. PMID: 27329840
    2. The ERK signaling pathway thus promotes cell motility through regulation of the subcellular localization of Myo1E. PMID: 27502487
    3. Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease. PMID: 25739341
    4. Myo1e is a key component contributing to the functional integrity of podocytes. PMID: 23977349
    5. MYO1E mutations are not a major cause of Chinese familial Steroid-resistant nephrotic syndrome. PMID: 24750828
    6. Homozygosity mapping and exome sequencing in a consanguineous kindred identified MYO1E and NEIL1 as novel candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome. PMID: 21697813
    7. MYO1E mutations are associated with childhood-onset, glucocorticoid-resistant focal segmental glomerulosclerosis. PMID: 21756023
    8. myo1e binds lipids through nonspecific electrostatic interactions rather than a stereospecific protein-phosphoinositide interaction. PMID: 20860408
    9. The kinetic mechanism of Myo1e (human myosin-IC). PMID: 11940582
    10. Two proteins with prominent functions in endocytosis, synaptojanin-1 and dynamin, bind to the SH3 domain of human Myo1E. PMID: 17257598

    顯示更多

    收起更多

  • 相關疾病：
    Focal segmental glomerulosclerosis 6 (FSGS6)
  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle. Cell junction.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 組織特異性：
    Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes.
  • 數據庫鏈接：

    HGNC: 7599

    OMIM: 601479

    KEGG: hsa:4643

    STRING: 9606.ENSP00000288235

    UniGene: Hs.654506



主站蜘蛛池模板： 国产精品久久香蕉免费播放| 亚洲精品亚洲人成在线| 国产一区二区三区在线蜜桃| 三级理论中文字幕在线播放| 蜜桃mv在线播放免费观看视频| 影音先锋无码aⅴ男人资源站| 国模裸体无码xxxx视频| 夜晚被公侵犯的人妻深田字幕| 人妻无码熟妇乱又伦精品视频| 亚洲精品一线二线三线无人区 | 一区二区国产高清视频在线| 久久精品亚洲日本波多野结衣 | 国产久热精品无码激情 | 99国产精品无码| 日本极品少妇xxxx| 国产成人无码a区在线| 亚洲.日韩.欧美另类| 亚洲国产精品久久久久婷婷老年 | 久久不见久久见免费视频7| 久久久免费精品re6| 美女人妻激情乱人伦| 日韩免费无码专区精品观看 | 天天爽夜夜爽夜夜爽精品视频| 国内精品久久久久影视| 国产成人不卡无码免费视频| 国产又色又爽又黄刺激在线视频| 日本三级手机在线播放线观看| 国产午夜精品一二区理论影院| 亚洲国产成人久久综合| 国产激情视频一区二区三区| 日韩精品无码一区二区| 欧美人与动牲交app视频| 国产精品视频二区不卡| 在线a视频网站| 99精品视频一区在线观看| 任我爽橹在线视频精品583| 在线永久免费观看黄网站| 日韩 国产 变态另类 欧美| 无人去码一码二码三码区| 亚洲精品乱码久久久久久久久久久久 | 999成人精品视频在线|