在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYO18A Antibody

MYO18A Antibody

  • 中文名稱(chēng)：
    MYO18A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA856414LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA856414LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) MYO18A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MYO18A
  • 別名：
    MYO18A antibody; CD245 antibody; KIAA0216 antibody; MYSPDZ antibody; Unconventional myosin-XVIIIa antibody; Molecule associated with JAK3 N-terminus antibody; MAJN antibody; Myosin containing a PDZ domain antibody; Surfactant protein receptor SP-R210 antibody; SP-R210 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Unconventional myosin-XVIIIa protein (1849-2054AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，MYO18A Antibody (CSB-PA856414LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于MYO18A Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA856414LB01HU MYO18A Antibody, HRP conjugated ELISA
    FITC CSB-PA856414LC01HU MYO18A Antibody, FITC conjugated
    Biotin CSB-PA856414LD01HU MYO18A Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking. Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages. Strongly enhances natural killer cell cytotoxicity.
  • 基因功能參考文獻(xiàn)：
    1. Studies indicate that MYO18A is overexpressed in metastatic prostate cancer (PC-3) cells. PMID: 27528748
    2. Identification of the DNA-damage-induced Golgi response reveals an unexpected pathway through DNA-PK, GOLPH3, and MYO18A that regulates cell survival following DNA damage. PMID: 24485452
    3. PDZ module mediates direct binding of myosin-18A to GOLPH3, and this interaction in turn modulates the actin binding properties of the N-terminal extension. Thus, myosin-18A can act as an actin cross-linker with multiple regulatory modulators PMID: 23990465
    4. GOLPH3L differs critically from GOLPH3 in that it is largely unable to bind to MYO18A; data demonstrate that despite their similarities, unexpectedly, GOLPH3L antagonizes GOLPH3/MYO18A at the Golgi PMID: 23345592
    5. Myo18aalpha as a novel binding partner of ezrin; the Myo18aalpha/ezrin complex may facilitate B cell receptor-mediated signaling PMID: 21751808
    6. GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin (via MYO18A) to stretch and shape the Golgi to promote budding. PMID: 19837035
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    8. MYO18A is a novel binding partner of the PAK2/betaPIX/GIT1 complex and suggest that MYO18A may play an important role in regulating epithelial cell migration via affecting multiple cell machineries. PMID: 19923322
    9. this dimeric myosin might stably cross-link actin filaments by two ATP-insensitive actin-binding sites at the N-terminal domains for higher-order organization of the actin cytoskeleton PMID: 15835906
    10. MyoXVIIIA constitutes a novel receptor for SP-A PMID: 16087679
    11. These findings support the hypothesis that SP-A, via SP-R210, suppresses cell-mediated immunity against M. tuberculosis via a mechanism that up-regulates secretion of IL-10 and TGF-beta1.[SP-A receptor] PMID: 18443188
    12. Study used a DNA-based long-distance inverse PCR (LDI-PCR) to identify a new MYO18A-PDGFRB fusion gene in an Eos-MPN (eosinophilia-associated atypical myeloproliferative neoplasms) with associated t(5;17)(q33-34;q11.2). PMID: 19006078

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Golgi apparatus. Golgi apparatus, trans-Golgi network. Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center.; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasm, cytoskeleton.; [Isoform 2]: Cytoplasm.; [Isoform 5]: Cell surface.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 31104

    OMIM: 609517

    KEGG: hsa:399687

    STRING: 9606.ENSP00000437073

    UniGene: Hs.462590



主站蜘蛛池模板： 久久伊人色av天堂九九| 秋霞午夜久久午夜精品| 国产成人无码精品久久久性色 | 中文字幕一区二区三区精彩视频| 国产无套乱子伦精彩是白视频| 免费视频爱爱太爽了| 亚洲精品无码成人片| 色婷婷亚洲精品综合影院| 中文国产成人精品久久app| 蜜桃臀无码内射一区二区三区| 国产精品久久久久久无码| 丰满爆乳在线播放| 日本真人边吃奶边做爽免费视频| 中文字幕在线精品视频| 久久久精品国产免大香伊| 日韩免费特黄一二三区| 免费人成视频网站在线下载| 无码人妻在线一区二区三区免费| 久久香蕉国产线看观看猫咪av| 顶级欧美熟妇xx| 国产成人av无码精品天堂| 伊人无码一区二区三区| 国产亚洲精品久久一区二区| 两个人看的www免费视频中文| 狠狠色噜噜狠狠狠狠777米奇| 激情综合激情五月俺也去| 国产精品亚洲а∨天堂| 男女啪啪永久免费网站| 国产女人被狂躁到高潮小说| 成人毛片无码免费播放网站| 日本欧美一区二区三区在线播放| 亚洲愉拍二区一区三区| 无码人妻熟妇av又粗又大| 国内精品卡一卡二卡三| 亚洲综合天堂一区二区三区| 日本成本人片免费网站| 无码人妻精品一区二区蜜桃百度| 精品国产杨幂在线观看| 国产亚洲日本精品无码| 四虎影视在线影院在线观看免费视频| 好男人社区资源|