在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYO18A Antibody

MYO18A Antibody

  • 中文名稱(chēng)：
    MYO18A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA856414LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA856414LA01HU diluted at 1:200 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) MYO18A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MYO18A
  • 別名：
    MYO18A antibody; CD245 antibody; KIAA0216 antibody; MYSPDZ antibody; Unconventional myosin-XVIIIa antibody; Molecule associated with JAK3 N-terminus antibody; MAJN antibody; Myosin containing a PDZ domain antibody; Surfactant protein receptor SP-R210 antibody; SP-R210 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Unconventional myosin-XVIIIa protein (1849-2054AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，MYO18A Antibody (CSB-PA856414LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于MYO18A Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA856414LB01HU MYO18A Antibody, HRP conjugated ELISA
    FITC CSB-PA856414LC01HU MYO18A Antibody, FITC conjugated
    Biotin CSB-PA856414LD01HU MYO18A Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking. Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages. Strongly enhances natural killer cell cytotoxicity.
  • 基因功能參考文獻(xiàn)：
    1. Studies indicate that MYO18A is overexpressed in metastatic prostate cancer (PC-3) cells. PMID: 27528748
    2. Identification of the DNA-damage-induced Golgi response reveals an unexpected pathway through DNA-PK, GOLPH3, and MYO18A that regulates cell survival following DNA damage. PMID: 24485452
    3. PDZ module mediates direct binding of myosin-18A to GOLPH3, and this interaction in turn modulates the actin binding properties of the N-terminal extension. Thus, myosin-18A can act as an actin cross-linker with multiple regulatory modulators PMID: 23990465
    4. GOLPH3L differs critically from GOLPH3 in that it is largely unable to bind to MYO18A; data demonstrate that despite their similarities, unexpectedly, GOLPH3L antagonizes GOLPH3/MYO18A at the Golgi PMID: 23345592
    5. Myo18aalpha as a novel binding partner of ezrin; the Myo18aalpha/ezrin complex may facilitate B cell receptor-mediated signaling PMID: 21751808
    6. GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin (via MYO18A) to stretch and shape the Golgi to promote budding. PMID: 19837035
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    8. MYO18A is a novel binding partner of the PAK2/betaPIX/GIT1 complex and suggest that MYO18A may play an important role in regulating epithelial cell migration via affecting multiple cell machineries. PMID: 19923322
    9. this dimeric myosin might stably cross-link actin filaments by two ATP-insensitive actin-binding sites at the N-terminal domains for higher-order organization of the actin cytoskeleton PMID: 15835906
    10. MyoXVIIIA constitutes a novel receptor for SP-A PMID: 16087679
    11. These findings support the hypothesis that SP-A, via SP-R210, suppresses cell-mediated immunity against M. tuberculosis via a mechanism that up-regulates secretion of IL-10 and TGF-beta1.[SP-A receptor] PMID: 18443188
    12. Study used a DNA-based long-distance inverse PCR (LDI-PCR) to identify a new MYO18A-PDGFRB fusion gene in an Eos-MPN (eosinophilia-associated atypical myeloproliferative neoplasms) with associated t(5;17)(q33-34;q11.2). PMID: 19006078

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Golgi apparatus. Golgi apparatus, trans-Golgi network. Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center.; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasm, cytoskeleton.; [Isoform 2]: Cytoplasm.; [Isoform 5]: Cell surface.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 31104

    OMIM: 609517

    KEGG: hsa:399687

    STRING: 9606.ENSP00000437073

    UniGene: Hs.462590



主站蜘蛛池模板： 无遮挡午夜男女xx00动态| 色爽黄1000部免费软件下载| 国产av无码专区国产乱码| 无码尹人久久相蕉无码| 猫咪www免费人成网站无码| 成人啪精品视频网站午夜| 人成午夜大片免费视频| 欧美成人a在线网站| 国产不卡视频一区二区三区| 免费裸体黄网站18禁免费| 国产啪精品视频网站免| 精品亚洲成a人无码成a在线观看| 一个人在线观看免费中文www| 强开小婷嫩苞又嫩又紧视频韩国 | 日韩放荡少妇无码视频| 18禁美女裸体无遮挡网站| 无码中文av有码中文av| 国产精品边做奶水狂喷无码| 亚洲精品区午夜亚洲精品区| 欧美黑人xxxx高潮猛交| 人妻丰满熟妇av无码区不卡| 国内精品久久久久影院蜜芽| 亚洲成_人网站图片| 免费人成视频在线播放| 亚洲日韩av无码一区二区三区| 欧洲 亚洲 国产图片综合 | 精品一区二区国产在线观看| 最新亚洲中文av在线不卡| 成人爽a毛片免费| 无码高潮少妇毛多水多水免费| av无码一区二区二三区1区6区| 久久精品国产亚洲αv忘忧草| 亚洲日韩成人无码| 精品人妻一区二区三区四区在线| 国产亚洲精品第一综合另类灬| 无码国产精成人午夜视频| 777午夜福利理论电影网| 天天狠天天天天透在线| 亚洲性色av性色在线观看| 在线视频观看免费视频18 | 久久久久蜜桃精品成人片|