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MTX1 Antibody

  • 中文名稱:
    MTX1兔多克隆抗體
  • 貨號:
    CSB-PA621679ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: MTX1 antibody at 3.78µg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: A549 whole cell lysate
      Lane 3: HepG2 whole cell lysate
      Lane 4: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 52, 48, 36 kDa
      Observed band size: 52, 36 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MTX1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MTX1
  • 別名:
    MTX1; MTX; MTXN; Metaxin-1; Mitochondrial outer membrane import complex protein 1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Metaxin-1 protein (217-466AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in transport of proteins into the mitochondrion. Essential for embryonic development.
  • 基因功能參考文獻:
    1. after the induction of apoptosis, Bak switches from its association with Mtx2 and VDAC2 to a closer association with Mtx1. PMID: 27845183
    2. Results describe the association between the MTX1 and beta-glucocerebrosidase genes and its possible effect on Parkinson disease. PMID: 21837367
    3. Single Nucleotide Polymorphism in metaxin 1 is associated with Gaucher disease PMID: 15024629
    4. The pathway of Voltage-dependent anion-selective channel biogenesis in human mitochondria involves the TOM complex, Sam50 and metaxins, and that it is evolutionarily conserved. PMID: 17510655
    5. mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330

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  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein. Mitochondrion outer membrane.
  • 蛋白家族:
    Metaxin family
  • 數據庫鏈接:

    HGNC: 7504

    OMIM: 600605

    KEGG: hsa:4580

    STRING: 9606.ENSP00000357360

    UniGene: Hs.490874



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