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MTERF4 Antibody, Biotin conjugated

  • 中文名稱:
    MTERF4兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA800224LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MTERF4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MTERF4
  • 別名:
    FLJ16261 antibody; HSPC096 antibody; MGC61716 antibody; MTER2_HUMAN antibody; MTERF domain containing 2 antibody; mTERF domain-containing protein 2 antibody; Mterfd2 antibody; OTTHUMP00000200479 antibody; OTTHUMP00000200519 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transcription termination factor 4, mitochondrial protein (45-87AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S).
  • 基因功能參考文獻:
    1. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease. PMID: 27894840
    2. analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex PMID: 22949673
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    MTERF family
  • 數據庫鏈接:

    HGNC: 28785

    OMIM: 615393

    KEGG: hsa:130916

    STRING: 9606.ENSP00000241527

    UniGene: Hs.159556



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