在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MSRB2 Antibody, Biotin conjugated

MSRB2 Antibody, Biotin conjugated

  • 中文名稱：
    MSRB2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA896505HD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MSRB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MSRB2
  • 別名：
    Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14), MSRB2, CBS-1 MSRB
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Methionine-R-sulfoxide reductase B2, mitochondrial protein (21-182aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
  • 基因功能參考文獻：
    1. this study we have identified, for the first time, compounds structurally related to the natural products fusaricidins that markedly activate recombinant bovine and human MsrA and human MsrB. PMID: 26718410
    2. Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress. PMID: 23988788
    3. the mitochondrial methionine-R-sulfoxide reductase B2 (MSRB2) is a specific interaction partner of LG72. PMID: 25078755
    4. Data show that glutaredoxin acts as a reductant for methionine sulfoxide reductases A and B (MsrA and MsrB) with or without resolving cysteine. PMID: 22634633
    5. CBS1, a methionine sulfoxide reductase of type B, is most abundant in muscle tissues, especially in the heart and thereby shows an expression pattern different to the human methionine sulfoxide reductase A PMID: 12220640
    6. MSRB is down-regulated during cell aging. PMID: 14759519
    7. hMSRB2 expression was weak in brain, but strong in heart, skeletal muscle, and smooth muscle-containing organs (digestive system, bladder), lung and aorta, while hMSRB1 displayed a higher expression in liver and kidney PMID: 14980072
    8. showed the expression and function of both sulfoxide reductases together with thioredoxin reductase in the cytosol as well as in the nucleus of epidermal melanocytes which are especially sensitive to reactive oxygen PMID: 16480945
    9. Methionine sulfoxide reductases A and B are seriously affected by hydrogen peroxide accumulation in acute vitiligo. PMID: 17943184
    10. upon oxidative stress, the overexpression of methionine sulfoxide reductase B2 leads to the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role PMID: 18424444
    11. almost absent catalase and methionine sulfoxide reductase A and B protein expression in human gray/white scalp hair shafts in association with a functional loss of methionine sulfoxide repair in the entire gray hair follicle PMID: 19237503
    12. MSR enzymes are differentially expressed in human skin. PMID: 19542914

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    MsrB Met sulfoxide reductase family
  • 組織特異性：
    Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
  • 數據庫鏈接：

    HGNC: 17061

    OMIM: 613782

    KEGG: hsa:22921

    STRING: 9606.ENSP00000365693

    UniGene: Hs.461420



主站蜘蛛池模板： 自慰小少妇毛又多又黑流白浆| 国产女人高潮视频在线观看| 久久精品国产一区二区三区| 一二三区乱码不卡手机版| 人妻少妇乱子伦无码专区| 国产熟妇另类久久久久久| 国产内射一区亚洲| 欧美人禽zozo动人物杂交| 熟女少妇丰满一区二区| 88国产精品视频一区二区三区| 国产成人小视频| 久久综合九色综合欧美就去吻| 欧洲亚洲国产成人综合色婷婷| 2021最新国产在线人成| 亚洲欧美黑人深喉猛交群| 国产在线国偷精品产拍| 97碰碰碰人妻无码视频| 中文字幕热久久久久久久| 亚洲另类欧美综合在线| 色偷偷www.8888在线观看| 久久久久久无码av成人影院| 久久国产精品久久精品国产| 亚洲日本中文字幕天天更新| 国产极品美女到高潮无套| 免费人成在线观看视频无码 | 日本内射精品一区二区视频 | 国产av一区二区三区天堂综合网| 97久久婷婷五月综合色d啪蜜芽| 国产下药迷倒白嫩美女网站| 无码国产69精品久久久久网站| 国产熟女一区二区三区四区五区| 亚洲精品字幕| 啪啪后入内射日韩| 成人午夜亚洲精品无码区| 国产日韩精品中文字无码| 女人被狂爆到高潮免费视频 | 久热爱精品视频线路一| 国产热re99久久6国产精品首页 | 日本高清色倩视频在线观看| 亚洲欧美日韩成人一区| 蜜臀av综合网|