在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MSRA Antibody, FITC conjugated

  • 中文名稱:
    MSRA兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA883456LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MSRA Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MSRA
  • 別名:
    Cytosolic methionine S sulfoxide reductase antibody; Methionine sulphoxide reductase A antibody; Mitochondrial peptide methionine sulfoxide reductase antibody; MSR A antibody; msrA antibody; MSRA_HUMAN antibody; peptide met (O) reductase antibody; Peptide Met(O) reductase antibody; Peptide methionine (S) S oxide reductase antibody; Peptide-methionine (S)-S-oxide reductase antibody; PMSR antibody; Protein methionine S oxide reductase antibody; Protein-methionine-S-oxide reductase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Mitochondrial peptide methionine sulfoxide reductase protein (24-235AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  • 基因功能參考文獻:
    1. Data show that miR-193b, by directly targeting focal adhesion kinase (FAK), CRK-like proto-oncogene (CRKL), and methionine sulfoxide reductase A (MSRA), regulates focal adhesion signaling and ROS signaling, which play pivotal roles in liposarcomagenesis and adipogenic differentiation. PMID: 28882999
    2. this study we have identified, for the first time, compounds structurally related to the natural products fusaricidins that markedly activate recombinant bovine and human MsrA and human MsrB. PMID: 26718410
    3. The association of MsrA haplotypes with executive functions indicated that MsrA is associated with executive function defects in bipolar I disorder patients. PMID: 26117066
    4. Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress. PMID: 23988788
    5. ARD1 has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA. PMID: 25341044
    6. The functional MSRA rs10903323 G/A polymorphism is associated with coronary artery disease development. PMID: 23880405
    7. We hypothesize that the activity of MsrA can be employed as a marker for the isolation of stem and progenitor cell subpopulations for cell therapy applications. PMID: 23415806
    8. The MSRA rs10903323 G/A variant allele is associated with Rheumatoid Arthritis development, especially among male patients, older patients, C-Reactive Protein-positive patients, and anti-cyclic citrullinated peptide negative patients. PMID: 23244167
    9. The MSRA rs10903323 gene polymorphism may be implicated in the increased risk to develop cardiovascular events, in particular ischaemic heart disease, observed in rheumatoid arthritis patients. PMID: 22657383
    10. Mammalian and yeast MSRA reduced free methionine sulfoxide much more efficiently than MSRB. PMID: 22867795
    11. Data show that glutaredoxin acts as a reductant for methionine sulfoxide reductases A and B (MsrA and MsrB) with or without resolving cysteine. PMID: 22634633
    12. The haplotype with the lowest P value showed association with Meconium ileus in an independent sample of 1,335 unrelated cystic fibrosis patients PMID: 22438829
    13. The MSRA gene located on chromosome 8 was found to be associated with the phenotype of schizophrenia in Chinese first-episode schizophrenia patients. PMID: 21679298
    14. central obesity-associated variants in LYPLAL1, NRXN3, MSRA, and TFAP2B PMID: 21674055
    15. Data suggest a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract. PMID: 21079812
    16. Our findings indicate that a novel association in the MSRA gene is related to oxidative stress and support the notion of a major role for this process in rheumatoid arthritis. PMID: 20617525
    17. reduction of MsrA levels results in increased cell proliferation and extracellular matrix degradation, and consequently in a more aggressive cellular phenotype in breast cancer cells PMID: 20937881
    18. Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20421936
    19. Dual sites of protein initiation control the localization and myristoylation of methionine sulfoxide reductase A PMID: 20368336
    20. protein-specific autoantibody are associated with pulmonary fibrosis and renal vascular damage in systemic sclerosis PMID: 19844733
    21. FOXO3a directly activates the human MsrA promoter in a cell culture system, implying that this could be a conserved mechanism of MsrA regulation. PMID: 19747232
    22. MSRA is down-regulated during cell aging. PMID: 14759519
    23. MsrA is present throughout the human lens, where it is likely to defend lens cells and their components against methionine oxidation PMID: 15199188
    24. The cloning and characterization of the 5' promoter region of human msrA are reported. PMID: 16162094
    25. MsrA may play an important role in cellular defenses against oxidative stress and in protection against death by limiting the accumulation of oxidative damage to proteins PMID: 16257642
    26. showed the expression and function of both sulfoxide reductases together with thioredoxin reductase in the cytosol as well as in the nucleus of epidermal melanocytes which are especially sensitive to reactive oxygen PMID: 16480945
    27. MSRA gene on chromosome 8p might possess metastasis suppressor activity in HCC. PMID: 17784942
    28. Methionine sulfoxide reductases A and B are seriously affected by hydrogen peroxide accumulation in acute vitiligo. PMID: 17943184
    29. this work points towards MSRA as a novel schizophrenia candidate gene PMID: 18506707
    30. Retinoic acid regulates transcription of MSRA gene via two distinct promoters via retinoic acid receptors. PMID: 18845237
    31. This suggests an important role for an MSRA catalytic antioxidant cycle for protection of the cytoplasmic compartment against oxidative damage. PMID: 19085252
    32. almost absent catalase and methionine sulfoxide reductase A and B protein expression in human gray/white scalp hair shafts in association with a functional loss of methionine sulfoxide repair in the entire gray hair follicle PMID: 19237503
    33. MSR enzymes are differentially expressed in human skin PMID: 19542914
    34. TFAP2B, LYPLAL1 and MSRA are associated with adiposity and fat distribution. PMID: 19557161
    35. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19557161

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 5]: Cytoplasm. Membrane; Lipid-anchor.
  • 蛋白家族:
    MsrA Met sulfoxide reductase family
  • 組織特異性:
    Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus.
  • 數據庫鏈接:

    HGNC: 7377

    OMIM: 601250

    KEGG: hsa:4482

    STRING: 9606.ENSP00000313921

    UniGene: Hs.490981



主站蜘蛛池模板: 国产尤物av尤物在线看| 亚洲日韩在线a视频在线观看| 大香线蕉伊人精品超碰| 成人美女黄网站色大色费全看 | 人妻熟妇乱又伦精品视频中文字幕| 无码无遮挡又大又爽又黄的视频| 2022久久国产精品免费热麻豆| 亚洲中文字幕不卡无码| 在线观看片免费人成视频无码| 国产女人乱人伦精品一区二区| 成人免费无码av| 四房播播开心五月| 久久国产福利一区二区| 久久理论片午夜琪琪电影院| 亚洲精品久久久久中文字幕二区| 久久综合精品国产二区无码| 久久综合狠狠色综合伊人| 国产在线观看黄av免费| 五月丁香六月综合缴情在线| 三级特黄60分钟在线观看| 人妻丰满熟妇av无码区乱| 日本老妇人乱xxy| 久久精品国产亚洲欧美成人 | 亚洲欧美乱综合图片区小说区 | 精品人妻潮喷久久久又裸又黄| 午夜视频在线瓜伦| 暖暖 在线 日本 免费 中文| 2018年亚洲欧美在线v| 亚洲一区在线日韩在线尤物| 亚洲成av人片在线观看无| 亚洲另类无码一区二区三区| 一本丁香综合久久久久不卡网站 | 少妇人妻av毛片在线看| 亚洲最新无码成av人| 蜜臀久久99精品久久久久久小说| 午夜福利伦伦电影理论片在线观看| 波多野结衣50连登视频| 国产精品白浆在线观看免费 | 欧美人妻少妇精品久久黑人| 精品国产制服丝袜高跟| 国产一区二区在线影院|