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  4. MRPS27 Antibody

MRPS27 Antibody

  • 中文名稱：
    MRPS27兔多克隆抗體
  • 貨號：
    CSB-PA003310
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using MRP-S27 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    28S ribosomal protein S27 antibody; 28S ribosomal protein S27, mitochondrial antibody; KIAA0264 antibody; Mitochondrial 28S ribosomal protein S27 antibody; mitochondrial antibody; mitochondrial ribosomal protein S27 antibody; MRP-S27 antibody; MRPS27 antibody; RT27_HUMAN antibody; S27mt antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human MRP-S27.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth.
  • 基因功能參考文獻：
    1. we verified for the first time that mitochondrial ribosomal protein S23 expression was upregulated in hepatocellular carcinoma. High mitochondrial ribosomal protein S23 levels can predict poor clinical outcomes in hepatocellular carcinoma, and this protein plays a key role in tumor proliferation. Therefore, mitochondrial ribosomal protein S23 may be a potential therapeutic target for hepatocellular carcinoma. PMID: 28714366
    2. MRPS27 is required for mitochondrial protein synthesis PMID: 22841715
  • 亞細胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Mitochondrion-specific ribosomal protein mS27 family
  • 組織特異性：
    Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous.
  • 數據庫鏈接：

    HGNC: 14512

    OMIM: 611989

    KEGG: hsa:23107

    STRING: 9606.ENSP00000261413

    UniGene: Hs.482491



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