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MRPS18B Antibody

  • 中文名稱:
    MRPS18B兔多克隆抗體
  • 貨號:
    CSB-PA014892GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    MRPS18B
  • 別名:
    28S ribosomal protein S18-2 antibody; 28S ribosomal protein S18b antibody; 28S ribosomal protein S18b; mitochondrial antibody; C6orf14 antibody; DKFZp564H0223 antibody; HSPC 183 antibody; HSPC183 antibody; mitochondrial antibody; Mitochondrial ribosomal protein S18 2 antibody; Mitochondrial ribosomal protein S18B antibody; MRP S18 2 antibody; MRP S18 b antibody; MRP S18b antibody; MRP-S18-2 antibody; MRP-S18-b antibody; MRPS 18B antibody; MRPS18 2 antibody; Mrps18-b antibody; MRPS18B antibody; PTD017 antibody; RT18B_HUMAN antibody; S18amt antibody; S18mt-b antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MRPS18B
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Together, these data suggest that the S18-2 protein induces epithelial to mesenchymal cell transition through the TWIST2/E-cadherin signalling and, consequently, CXCR4-mediated migration of prostate cancer cells. PMID: 29396484
    2. Evolutionary trace analysis showed that the S18-2 protein is mutated at the higher rate in tumors, compared with S18-1 and S18-3. The one of the most conserved residues in the S18-2 protein sequence, Gly132, is often mutated in colorectal cancer. PMID: 27489352
    3. We conclude that high expression of S18-2 and free E2F...1might be a good set of prognostic markers for endometrial cancer PMID: 26959119
    4. Studies suggest that mitochondrial ribosomal protein S18-2 protein, together with the retinoblastoma protein (RB), plays a crucial role in the control on cell stemness and differentiation. PMID: 28361860
    5. S18-2 is a newly identified oncoprotein that may be involved in cancerogenesis PMID: 26023799
    6. EBNA-6 {ebna-3c} binds to MRPS18-2 , and targets it to the nucleus; binding targets the small pocket of pRb, which is a site of interaction with E2F1. The MRPS18-2 competes with the binding of E2F1 to pRb, thereby raising the level of free E2F1 PMID: 18391203

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  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    Bacterial ribosomal protein bS18 family, Mitochondrion-specific ribosomal protein mS40 subfamily
  • 數據庫鏈接:

    HGNC: 14516

    OMIM: 611982

    KEGG: hsa:28973

    STRING: 9606.ENSP00000259873

    UniGene: Hs.655329



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