在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MRPL58 Antibody

  • 中文名稱:
    MRPL58兔多克隆抗體
  • 貨號:
    CSB-PA613490HA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: MRPL58 antibody at 2µg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 24 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA613490HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA613490HA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MRPL58 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MRPL58
  • 別名:
    Digestion substraction 1 antibody; DS-1 antibody; DS1 antibody; Ict1 antibody; ICT1_HUMAN antibody; Immature colon carcinoma transcript 1 antibody; Immature colon carcinoma transcript 1 protein antibody; mitochondrial antibody; Peptidyl-tRNA hydrolase ICT1 antibody; Peptidyl-tRNA hydrolase ICT1, mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Peptidyl-tRNA hydrolase ICT1, mitochondrial protein (30-206AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,MRPL58 Antibody (CSB-PA613490HA01HU),的標記方式是Non-conjugated。對于MRPL58 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA613490HB01HU MRPL58 Antibody, HRP conjugated ELISA
    FITC CSB-PA613490HC01HU MRPL58 Antibody, FITC conjugated
    Biotin CSB-PA613490HD01HU MRPL58 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
  • 基因功能參考文獻:
    1. High ICT1 expression is associated with leukemia. PMID: 29328466
    2. ICT1 overexpression notably predicted poor prognosis of gastric cancer patients. PMID: 28987942
    3. Study demonstrates that ICT1 overexpression correlates with malignant clinical features and poor prognosis of hepatocellular carcinoma (HCC) patients. Functionally, ICT1 promotes proliferation, cell cycle progression and inhibits apoptosis of HCC cells. ICT1 regulates the expressions of CDK1, cyclin B1, Bcl-2 and Bax, and is directly targeted by microRNA-134 (miR-134) in HCC cells. PMID: 29130100
    4. ICT1 may play a crucial role in promoting gastric cancer proliferation in vitro. PMID: 29036264
    5. The results provide direct evidence that localized feedbacks on Fat4-Ds1 complexes can give rise to planar cell polarity. PMID: 28826487
    6. our preliminary study reveals the important role of ICT1 in NSCLC cells that knockdown of ICT1 significantly suppressed cell proliferation, arrested cell cycle though altering expression cell cycle regulators, and promoted cell apoptosis. PMID: 27413166
    7. ICT1 knockdown significantly inhibited cell proliferation and migration, led to G2/M phase cell-cycle arrest, and triggered apoptosis via the intracellular AMPKa, SAPK/JNK, and PARP signaling pathways. PMID: 27411551
    8. ICT1 was significantly upregulated in diffuse large B-cell lymphoma tissues (DLBCL) and correlated with poor survival. Knockdown of ICT1 remarkably induced cell cycle G0/G phase arrest and apoptosis in DLBCL cells. PMID: 28629825
    9. ICT1 knockdown altered the expression of apoptosis- or cell cyclerelated proteins such as Bcl-2, caspase-3, CDK1, CDK2 and cyclin B. PMID: 28290601
    10. ICT1 may be essential for hydrolysis of prematurely terminated peptidyl-tRNA moieties in stalled mitoribosomes. PMID: 20186120

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    Prokaryotic/mitochondrial release factor family, Mitochondrion-specific ribosomal protein mL62 subfamily
  • 組織特異性:
    Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.
  • 數據庫鏈接:

    HGNC: 5359

    OMIM: 603000

    KEGG: hsa:3396

    STRING: 9606.ENSP00000301585

    UniGene: Hs.407955



主站蜘蛛池模板: 性饥渴少妇av无码毛片| 亚洲精品无码你懂的| 免费无码又爽又刺激一高潮| 一个人看免费视频www| 强行从后面挺进人妻| 啪啪无码人妻丰满熟妇| 综合无码一区二区三区| 亚洲日韩成人性av网站| 国产又黄又潮娇喘视频在线观看| 久久婷婷五月综合色奶水99啪| 免费人成视频| 无码人妻精品一区二区三区66| 青青青国产精品国产精品美女| 天堂亚洲2017在线观看| 精品一区二区三区自拍图片区| 色偷偷亚洲男人本色| 久久久一本精品99久久精品66| 凸偷窥中国女人洗澡| 国产亚洲精品欧洲在线观看| ass日本丰满熟妇pics| 乱中年女人伦av| 亚洲孰妇无码av在线播放| 国产女人高潮抽搐喷水视频| 久9视频这里只有精品| 日日噜噜夜夜狠狠久久蜜桃| 全部露出来毛走秀福利视频| 中国老熟妇自拍hd发布| 一区二区免费高清观看国产丝瓜| 国产av麻豆mag剧集| 国语自产拍精品香蕉在线播放 | 吃奶呻吟打开双腿做受在线视频 | 国产v亚洲v天堂无码久久久| 久久这里只精品国产免费9| 免费不卡无码av在线观看| 亚洲伊人成无码综合网| 日本三级在线观看免费| 国产精品点击进入在线影院高清 | 亚洲国产成人精品无码区一本| 男女啪动最猛动态图| 人妻少妇被猛烈进入中文字幕| 国产第一页浮力影院入口|