在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MRM2 Antibody, Biotin conjugated

MRM2 Antibody, Biotin conjugated

  • 中文名稱：
    MRM2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA883420LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MRM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MRM2
  • 別名：
    FJH1 antibody; FTSJ2 antibody; MRM2 antibody; Protein ftsJ homolog 2 antibody; Putative ribosomal RNA methyltransferase 2 antibody; Ribosomal RNA methyltransferase 2 antibody; RRMJ2_HUMAN antibody; rRNA (uridine-2''-O-)-methyltransferase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human rRNA methyltransferase 2, mitochondrial protein (19-246AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
  • 基因功能參考文獻：
    1. Targeted exome sequencing of genes encoding the mitochondrial proteome identified a damaging mutation, c.567 G > A, affecting a highly conserved amino acid residue (p.Gly189Arg) of the MRM2 protein. Our findings establish that defective MRM2 causes a MELAS-like phenotype, and suggests the genetic screening of the MRM2 gene in patients with a m.3243 A > G negative MELAS-like presentation. PMID: 28973171
    2. miR-542-3p functions as a suppressor gene by targeting and upregulating FTSJ2, thus inhibiting the malignancy of non-small cell lung cancer cells PMID: 28866101
    3. MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome. PMID: 25009282
    4. Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively. PMID: 25074936
    5. FTSJ2 possesses suppressive effects on the invasion and migration of cancer cells. PMID: 24595062
    6. FTSJ2 is a nucleolar RNA methyltransferase involved in eukaryotic RNA processing and modification. PMID: 11827451

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, RNA methyltransferase RlmE family
  • 組織特異性：
    Widely expressed, with highest expression in muscle, placenta, and heart.
  • 數據庫鏈接：

    HGNC: 16352

    OMIM: 606906

    KEGG: hsa:29960

    STRING: 9606.ENSP00000242257

    UniGene: Hs.279877



主站蜘蛛池模板： 涩里番网污站| 久久日本三级韩国三级| 人妻人人澡人人添人人爽人人玩 | 国产精品久久人妻互换| 被灌满精子的波多野结衣| 丁香五香天堂网| 欧美成人免费全部观看国产| 色老头精品午夜福利视频| 真人与拘做受免费视频一| 亚洲第一女人av| 亚洲午夜成人久久久久久| 国产欧美一区二区精品仙草咪 | 小宝贝荡货啊用力水湿aⅴ视频| 又色又爽又黄的视频女女| 国产精品久久久久久久久绿色| 国产一三四2021不卡| 粉嫩被粗大进进出出视频| 毛片大全真人在线| 成人性生交大片免费卡看| 女的被弄到高潮娇喘喷水视频| 亚洲精品久久午夜无码一区二区 | 国产性生交xxxxx免费| 国产gv在线观看受被做哭| 久久久久久无码精品人妻a片软件| 玩弄少妇人妻中文字幕| 九一九色国产| 亚洲另类自拍丝袜第五页| 亚洲一区二区三区在线网址| 67194熟妇在线观看线路| 亚洲日韩激情无码一区| 国产乱人伦偷精品视频下| 男女下面一进一出无遮挡| 久久不见久久见中文字幕免费| 亚洲另类欧美综合在线| 国产美女遭强高潮网站下载| 女人与拘做受全过程免费视频| 国产在线一区二区av视频| 国产黑色丝袜视频在线观看网红| 久久99亚洲精品久久久久| 国产精品无码天天爽视频| 国产又色又爽又黄的|