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  4. MRGPRX3 Antibody, FITC conjugated

MRGPRX3 Antibody, FITC conjugated

  • 中文名稱：
    MRGPRX3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA850382LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MRGPRX3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    G protein coupled receptor SNSR1 antibody; G protein coupled receptor SNSR2 antibody; G protein-coupled receptor MRGX 3 antibody; G protein-coupled receptor MRGX3 antibody; GPCR antibody; Mas related GPCR member X3 antibody; Mas-related G protein coupled MRGX 3 antibody; Mas-related G protein coupled MRGX3 antibody; Mas-related G-protein coupled receptor member X3 antibody; MAS-related GPR, member X3 antibody; MRGPRX3 antibody; MRGX3 antibody; MRGX3_HUMAN antibody; Sensory neuron-specific G-protein coupled receptor 1 antibody; Sensory neuron-specific G-protein coupled receptor 1/2 antibody; SNSR1 antibody; SNSR2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mas-related G-protein coupled receptor member X3 protein (276-322AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.
  • 基因功能參考文獻：
    1. Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID: 29408502
    2. Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID: 28189739
    3. overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID: 15809047
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Mas subfamily
  • 組織特異性：
    Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
  • 數據庫鏈接：

    HGNC: 17980

    OMIM: 607229

    KEGG: hsa:117195

    STRING: 9606.ENSP00000379571

    UniGene: Hs.380177



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