在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MREG Antibody, FITC conjugated

  • 中文名稱:
    MREG兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA014788LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MREG Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MREG
  • 別名:
    MREG antibody; DSU antibody; HDCGA21P antibody; Melanoregulin antibody; Dilute suppressor protein homolog antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Melanoregulin protein (1-214AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery. Plays a role in hair pigmentation, a process that involves shedding of melanosome-containing vesicles from melanocytes, followed by phagocytosis of the melanosome-containing vesicles by keratinocytes. Functions on melanosomes as receptor for RILP and the complex formed by RILP and DCTN1, and thereby contributes to retrograde melanosome transport from the cell periphery to the center. Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell. Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport. Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate and phosphatidylinositol 3,5-bisphosphate, but not phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 4,5-bisphosphate. Required for normal phagosome clearing and normal activation of lysosomal enzymes in lysosomes from retinal pigment epithelium cells. Required for normal degradation of the lipofuscin component N-retinylidene-N-retinylethanolamine (A2E) in the eye. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells.
  • 基因功能參考文獻:
    1. Taken together, MREG regulates thyroid cancer cell invasion and proliferation through PI3K/Akt-mTOR signaling pathway. MREG may serve as a promising therapeutic strategy for thyroid cancer. PMID: 28698135
    2. MREG-dependent processing links both autophagic and phagocytic processes in LC3-associated phagocytosis. MREG participates in coordinating the association of phagosomes with LC3 for content degradation with the MREG loss leading to phagosome accumulation. PMID: 25301234
  • 亞細胞定位:
    Apical cell membrane; Peripheral membrane protein. Melanosome membrane; Lipid-anchor. Lysosome membrane; Lipid-anchor. Cytoplasmic vesicle membrane.
  • 蛋白家族:
    Melanoregulin family
  • 組織特異性:
    Expressed in photoreceptor cells (at protein level).
  • 數據庫鏈接:

    HGNC: 25478

    OMIM: 609207

    KEGG: hsa:55686

    STRING: 9606.ENSP00000263268

    UniGene: Hs.620391



主站蜘蛛池模板: 国产制服丝袜亚洲高清| 嫩草av久久伊人妇女超级a| 国产精品无码翘臀在线观看| 久久精品黄aa片一区二区三区| 99j久久精品久久久久久| 午夜亚洲国产理论片中文飘花| 国产精品门事件av| 黑人大荫蒂老太大| 乱中年女人伦av| 国产成人精品无码一区二区三区| 婷婷丁香五月缴情视频| 国产精品老热丝在线观看| 色悠久久久久综合网香蕉| 国产亚洲999精品aa片在线爽| 露脸内射熟女--69xx| 老熟女高潮一区二区三区| 又色又爽又高潮免费观看| 久久www成人影院| 精品乱人伦一区二区三区 | 男人的天堂av社区在线| av一区二区国产在线视频| 日韩一欧美内射在线观看| 久久精品中文无码资源站| 伊人伊成久久人综合网996| 久久香蕉国产线看观看猫咪av| 99久久久国产精品免费蜜臀| 国产99视频精品免费专区 | 午夜福利理论片在线观看播放| 亚洲人成电影网站色| 无码专区手机在线播放| 成人亚洲性情网站www在线观看 | 高潮内射免费看片| 天堂а√中文在线| 免费国产裸体美女视频全黄| 国产精品久久久久7777| 色天使亚洲综合一区二区| 精品无码专区亚洲| 又大又粗欧美黑人aaaaa片| 浪荡女天天不停挨cao日常视频| av天堂午夜精品蜜臀av| 色综合中文综合网|