在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MPS1 Antibody

MPS1 Antibody

Rare Species
  • 中文名稱：
    MPS1 Antibody
  • 貨號：
    CSB-PA346524XA01SVG
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: MPS1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 47 kDa
      Observed band size: 47 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MPS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MPS1
  • 別名：
    Serine/threonine-protein kinase MPS1 (EC 2.7.12.2) (Monopolar spindle protein 1) (Regulatory cell proliferation kinase 1) MPS1 RPK1 YDL028C D2785
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Saccharomyces cerevisiae (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (Baker's yeast) MPS1 protein (40-289aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation. Implicated in spindle pole body (SPD) duplication. Dual specificity kinase that can phosphorylate serine, threonine and tyrosine residues. Phosphorylates the SPC29 and SPC110 spindle pole body components.
  • 基因功能參考文獻(xiàn)：
    1. An important role for Mps1 phosphorylation in the spindle assembly checkpoint activation, beyond the direct recruitment of Mad1 and Mad2. PMID: 27280788
    2. CCT271850 is a potent, selective and orally bioavailable MPS1 kinase inhibitor. On the basis of in vivo pharmacodynamic vs efficacy relationships, we predict that more than 80% inhibition of MPS1 activity for at least 24 h is required to achieve tumour stasis or regression by CCT271850. PMID: 28334731
    3. These findings highlight MPS1 as a rational therapeutic target for medulloblastoma PMID: 27633003
    4. Disrupting Mps1 before mitotic entry reduces chromosomal passenger complex (CPC) localization to the centromere. Mps1 plays a minimal role in maintaining CPC localization once cells are in mitosis. PMID: 25854549
    5. Mps1 kinase controls Cnn1 localization and activity at kinetochores through the cell cycle. PMID: 25716979
    6. Ipl1 released these improper connections, whereas Mps1 triggered the formation of new force-generating microtubule attachments. PMID: 23371552
    7. found that Sgo1 overexpression rescues defects caused by metaphase inactivation of Mps1 and that Mps1 is required for Sgo1 localization to the kinetochore PMID: 21389114
    8. Mps1 plays an important role in kinetochore attachment during mitotic spindle assembly and function. PMID: 15668173
    9. it was demonstrated that mutual inhibition between the anaphase-promoting complex (APC) and Mps1, an essential component of the checkpoint, leads to sustained inactivation of the spindle checkpoint PMID: 16825537
    10. Phosphorylation of Dam1 residues S218 and S221 by Mps1 is required for efficient coupling of kinetochores to microtubule plus ends. PMID: 16890524
    11. Mps1 promotes re-orientation of kinetochore-spindle pole connections and eliminates those that do not generate tension between sister kinetochores. PMID: 18060784
    12. Results suggest that a putative Mps1-dependent phosphorylation of Ndc80 is important for spindle assembly checkpoint activation at kinetochores. PMID: 19300438

    顯示更多

    收起更多

  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 數(shù)據(jù)庫鏈接：

    KEGG: sce:YDL028C

    STRING: 4932.YDL028C



主站蜘蛛池模板： 国产成人精品午夜福利在线观看| 欧美va亚洲va在线观看日本| 性高湖久久久久久久久aaaaa| 日韩人妻无码免费视频一区二区| 欧美人与动牲交免费观看网| 国产在线无码视频一区二区三区| 亚洲国产成人爱av在线播放| 国产麻豆乱子伦午夜视频观看| 人妻教师痴汉电车波多野结衣 | 中文字幕乱码人妻一区二区三区 | 狠狠亚洲狠狠欧洲2019| 亚洲欧美日产综合在线| 色欲天天天无码视频| 亚洲欧洲精品a片久久99| 免费毛片手机在线播放| 亚洲大成色www永久网站动图| 在阳台上玩弄人妻的乳球| 疯狂做受xxxx高潮不断| 欧美人与动牲交zooz乌克兰| 国产精品久久久久久久| 亚洲综合无码精品一区二区三区 | av天堂午夜精品蜜臀av| 国产剧情无码播放在线观看| 亚洲欧美国产制服图片区| 好男人在在线社区www在线影院 | 青青草国产精品欧美成人| 亚洲中文字幕乱码av波多ji| 亚洲欧美日韩中文播放| 日韩丝袜欧美人妻制服| 国产成+人+综合+亚洲欧美丁香花| 日韩在线一区二区三区免费视频| 99精品国产再热久久无毒不卡| 无码人妻丰满熟妇精品区| 国产欧美精品一区二区三区-老狼| 性大毛片视频| 欧洲多毛裸体xxxxx| 人妻夜夜爽天天爽三区麻豆av网站 | 久久久久国产精品嫩草影院| 亚洲中文字幕无码永久在线| 啦啦啦www播放日本观看 | 亚洲风影视传媒有限公司辽宁|