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MPP1 Antibody, FITC conjugated

  • 中文名稱:
    MPP1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA014758LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MPP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MPP1
  • 別名:
    55 kDa erythrocyte membrane protein antibody; AAG 12 antibody; AAG12 antibody; Aging associated gene 12 antibody; DXS552 antibody; DXS552E antibody; EM55_HUMAN antibody; EMP 55 antibody; EMP55 antibody; Erythrocyte membrane protein p55 antibody; Membrane protein antibody; Membrane protein palmitoylated 1 55kDa antibody; Membrane protein palmitoylated 1 antibody; Membrane protein; palmitoylated 1; 55kDa antibody; Migration related gene 1 antibody; MPP 1 antibody; MPP1 antibody; MRG 1 antibody; MRG1 antibody; OTTHUMP00000026054 antibody; OTTHUMP00000196176 antibody; p55 antibody; palmitoylated 1 antibody; Palmitoylated erythrocyte membrane protein antibody; Palmitoylated membrane protein 1 antibody; PEMP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human 55 kDa erythrocyte membrane protein (123-252AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
  • 基因功能參考文獻:
    1. Data suggest that targeting the ATP binding cassette subfamily C member 4 (ABCC4)-membrane palmitoylated protein 1 (MPP1) protein complex can lead to new therapies to improve treatment outcome of acute myeloid leukemia (AML). PMID: 29146910
    2. A new perspective on the role of MPP1 in erythroid cells suggests that direct MPP1-flotillins interactions could be the major driving-force behind the formation of raft domains in red blood cells. PMID: 28865798
    3. conclusion, the data demonstrates that MPP1 interacts with lipid mixtures in two different model membrane systems. PMID: 28653654
    4. Studies indicate that palmitoylated erythrocyte membrane protein p55 (MPP1) and its palmitoylation play a crucial role in lateral membrane organization in erythroid cells. PMID: 25408337
    5. MPP1 knockdown significantly affects the activation of MAP-kinase signaling. PMID: 23507198
    6. MPP1 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
    7. Results show the NMR-derived structure of the human erythroid p55 PDZ domain and propose a possible interaction mode with the C-terminus of glycophorin C. PMID: 16741958
    8. MPP1 links the Usher protein network and the Crumbs protein complex in the retina PMID: 17584769
    9. p55 binds to two distinct sites within the FERM domain, and the alternatively spliced exon 5 is necessary for the membrane targeting of protein 4.1R in epithelial cells. PMID: 18952129
    10. p55-NF2 protein interaction may play a functional role in the regulation of apico-basal polarity and tumor suppression pathways in non-erythroid cells. PMID: 19144871

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  • 亞細胞定位:
    Cell membrane; Lipid-anchor. Cell projection, stereocilium.
  • 蛋白家族:
    MAGUK family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 7219

    OMIM: 305360

    KEGG: hsa:4354

    STRING: 9606.ENSP00000358547

    UniGene: Hs.496984



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