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MOCS2 Antibody

  • 中文名稱：
    MOCS2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA014706ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: MOCS2 antibody at 0.47 μg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Lane 4: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 21 kDa
      Observed band size: 21, 49 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA014706ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA014706ESR2HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA014706ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MOCS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MOCS2
  • 別名：
    MOCS2 antibody; MCBPE antibody; MOCO1 antibody; Molybdopterin synthase catalytic subunit antibody; EC 2.8.1.12 antibody; MOCO1-B antibody; Molybdenum cofactor synthesis protein 2 large subunit antibody; Molybdenum cofactor synthesis protein 2B antibody; MOCS2B antibody; Molybdopterin-synthase large subunit antibody; MPT synthase large subunit antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Molybdopterin synthase catalytic subunit protein (1-188AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IP, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
  • 基因功能參考文獻(xiàn)：
    1. analysis of sites within MOCS2 where mutations cause molybdenum cofactor deficiency PMID: 12732628
    2. There was undisturbed production of both transcripts, while Western blot analysis demonstrated that MOCS2B, the large subunit, is unstable in the absence of MOCS2A. PMID: 16737835
    3. We reported here an infant with MoCD who presented with hypoxic ischaemic encephalopathy and identified a novel mutation, c.130C>T in cDNA of the MOCS2 gene from the infant. PMID: 17158010
  • 相關(guān)疾病：
    Molybdenum cofactor deficiency, complementation group B (MOCODB)
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    MoaE family, MOCS2B subfamily
  • 組織特異性：
    Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 7193

    OMIM: 252160

    KEGG: hsa:4338

    STRING: 9606.ENSP00000380157

    UniGene: Hs.163645



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