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  4. MOCOS Antibody

MOCOS Antibody

  • 中文名稱：
    MOCOS兔多克隆抗體
  • 貨號：
    CSB-PA014702GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MOCOS
  • 別名：
    MOCOS antibody; Molybdenum cofactor sulfurase antibody; MCS antibody; MOS antibody; MoCo sulfurase antibody; hMCS antibody; EC 2.8.1.9 antibody; Molybdenum cofactor sulfurtransferase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MOCOS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.
  • 基因功能參考文獻：
    1. MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH) and aldehyde oxidase 1 (AOX1), which is required for their activities. PMID: 22495427
    2. Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria. PMID: 17368066
  • 相關(guān)疾病：
    Xanthinuria 2 (XAN2)
  • 蛋白家族：
    Class-V pyridoxal-phosphate-dependent aminotransferase family, MOCOS subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18234

    OMIM: 603592

    KEGG: hsa:55034

    STRING: 9606.ENSP00000261326

    UniGene: Hs.405028



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