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  4. MINPP1 Antibody

MINPP1 Antibody

  • 中文名稱：
    MINPP1兔多克隆抗體
  • 貨號：
    CSB-PA039513
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from 293 cells, using MINPP1 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MINPP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MINPP1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human MINPP1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
  • 基因功能參考文獻(xiàn)：
    1. Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
    2. By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306
  • 相關(guān)疾病：
    Thyroid cancer, non-medullary, 2 (NMTC2)
  • 亞細(xì)胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Histidine acid phosphatase family, MINPP1 subfamily
  • 組織特異性：
    Widely expressed with highest levels in kidney, liver and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 7102

    OMIM: 188470

    KEGG: hsa:9562

    STRING: 9606.ENSP00000361064

    UniGene: Hs.121260



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