在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MIA Antibody

  • 中文名稱:
    MIA兔多克隆抗體
  • 貨號:
    CSB-PA613694LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA613694LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA613694LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MIA Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Cartilage derived retinoic acid sensitive protein antibody; CD RAP antibody; CDRAP antibody; Melanoma derived growth regulatory protein precursor antibody; Melanoma inhibitory activity protein antibody; Melanoma-derived growth regulatory protein antibody; Mia antibody; MIA_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Melanoma-derived growth regulatory protein (87-124AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,MIA Antibody (CSB-PA613694LA01HU),的標記方式是Non-conjugated。對于MIA Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA613694LB01HU MIA Antibody, HRP conjugated ELISA
    FITC CSB-PA613694LC01HU MIA Antibody, FITC conjugated
    Biotin CSB-PA613694LD01HU MIA Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
  • 基因功能參考文獻:
    1. the molecular basis of the interaction of MIA with the Hep II domain of fibronectin based on nuclear magnetic resonance spectroscopic binding assays. PMID: 28565914
    2. The frequency of MIA gene family expression was higher among squamous cell carcinomas than among other tumor types subjected to screening. MIA gene family staining was observed frequently in esophageal and lung cancers associated with nodal and/or distant metastasis. In cervical cancers, MIA and TANGO immunostaining also correlated with tumor progression and metastasis. PMID: 27145272
    3. Our results suggest that MIA-STOX2 signaling may be a useful diagnostic and therapeutic target in oral squamous cell carcinoma PMID: 27050375
    4. MIA had a slightly superior sensitivity to detect progressive disease compared to S100 and seems to be more useful in monitoring of patients with metastatic melanoma receiving immunotherapy PMID: 28870930
    5. real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B, the read-through long non-coding RNA (lncRNA), RAB4B, PIM2 and TAOK1 share common binding site of a microRNA, miR-24, in their 3'UTRs PMID: 28306719
    6. The effects of MIA/CD-RAP on transcriptional regulation in chondrocytes, through the regulation of p54(nrb) via YBX1 contributes to the understanding of chondrogenesis. PMID: 24349210
    7. data provide evidence for a critical role of SOX10 in melanoma cell invasion through the regulation of MIA and highlight its role as a therapeutic target in melanoma PMID: 24608986
    8. Focus on the quantitative analysis of the MIA protein as a prognostic tool because it has proven to be a useful serum marker for documenting disease progression of malignant melanoma. Review. PMID: 24372647
    9. Functional promoter analysis identified the transcription factor YBX1 as the mediator of MIA activation of p54(nrb) transcription. PMID: 23672612
    10. MIA protein is present in non-segmental vitiligo skin and may cause the detachment of melanocytes; its target is integrin alpha5beta1, which determines the breaking and/or weakening of connections among melanocytes and basal membrane PMID: 23664187
    11. Results show that S-100B, MIA and LDH levels were significantly higher in patients with advanced melanoma than in disease-free patients or healthy controls. PMID: 21858537
    12. assessed the utility of melanoma inhibitory activity (MIA) serum marker in the follow up and primary diagnosis of stage III melanoma patients PMID: 21658116
    13. Further diagnostics should be initiated in uveal melanoma patients with serum MIA above 8.3ng/ml. PMID: 21540751
    14. Data suggest that plasma markers: CEACAM, ICAM-1, osteopontin, MIA, TIMP-1 and S100B particularly when assessed in combination, can be used to monitor patients for disease recurrenc. PMID: 21487066
    15. The cell-specific production rate of MIA was quantitatively proportional to the aggrecan gene expression level in the early and middle phase of cartilage chondrocyte differentiation. PMID: 21277254
    16. MIA/CD-RAP stabilizes cartilage differentiation and inhibits differentiation into bone potentially by regulating signaling processes during differentiation. PMID: 20164682
    17. pancreatic cancer patients with high intratumoral expression are antibody-negative and have shorter survival PMID: 20514540
    18. A fluorescence polarization biological assay was developed using MIA protein-binding compounds for studies of the binding properties of this protein. PMID: 19852767
    19. The assignments, solution structure, & dynamics of human MIA were determined by heteronuclear NMR methods. The structure consists of an SH3-like subdomain with N- and C-terminal extensions of about 20 amino acids each that form a novel fold. PMID: 11991352
    20. Melanoma-inhibiting activity (MIA/CD-RAP) is expressed in a variety of malignant tumors of mainly neuroectodermal origin. PMID: 12014625
    21. expression pattern of a novel splice product MIA (splice) of malignant melanoma-derived growth-inhibiting activity (MIAY CD-RAP). PMID: 12230496
    22. Stable antisense-HMG1 expression in melanoma cells led to the reduction of melanoma inhibitory activity (MIA) promoter activity and protein expression. PMID: 12665595
    23. increased MIA production may, in turn, increase the invasive properties of the cells by modulating the attachment of human uveal melanoma cells to the extracellular matrix PMID: 15057037
    24. MIA may promote the detachment of radial and vertical growth phase melanomas. PMID: 15201995
    25. The MIA protein enhances the migration of melanocytes and promotes melanoma progression. PMID: 15208686
    26. MIA may contribute to immunosuppression frequently seen in malignant melanomas by inhibiting cellular antitumor immune reactions. PMID: 15386421
    27. MIA in homogenates of surgical specimen directly relate to a more benign clinical prognosis in patients with high-grade glioma PMID: 15547763
    28. There is a correlation between MIA expression and pigmentation and morphology of melanocytic cells. PMID: 15760338
    29. Increased levels of MIA is associated with gastric cancer PMID: 16331256
    30. When patients progressed, level of MIA increased significantly. PMID: 17348447
    31. A candidate autoantigen in rheumatoid arthritis found in synovial fluid cells. PMID: 17599744
    32. An antigen in melanoma, elevated in 22 per cent of patients, predicting recurrence. PMID: 17661202
    33. MIA serum level is the ideal test for screening the skin melanoma spread to sentinel lymph nodes. PMID: 18477894
    34. MIA expression is enhanced by the interaction of intracellular HMGB1 and NFkBp65 and MIA is closely involved in tumor progression and nodal metastasis by the increments of VEGF-C and VEGF-D in oral squamous cell carcinomas. PMID: 18616526
    35. MIA protein, binding to integrins and thus promoting detachment of cells from extracellular matrix structures, is internalized into the cell together with these cell adhesion receptors at the cell rear. PMID: 19521988

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    MIA/OTOR family
  • 組織特異性:
    All malignant melanoma cell lines tested and infrequently in glioma cell lines.
  • 數據庫鏈接:

    HGNC: 7076

    OMIM: 601340

    KEGG: hsa:8190

    STRING: 9606.ENSP00000263369

    UniGene: Hs.646364



主站蜘蛛池模板: 在线中文新版最新版在线| 国产精品最新免费视频| 日韩人妻中文无码一区二区七区| 亚洲精品自产拍在线观看| 国产真实自在自线免费精品| 久久青青草原精品国产app| 免费观看男女性高视频| 亚洲人亚洲人成电影网站色| 日本特黄特色aaa大片免费| 无码日韩精品一区二区免费| 一本久道高清无码视频| 在线综合亚洲欧洲综合网站| 亚洲中文有码字幕青青| 少妇极品熟妇人妻200片| 亚洲一区二区三区四区 | 新国产三级视频在线播放| 日韩视频在线观看| 精品国产杨幂在线观看| 激情文学小说区另类小说同性| 丰满少妇高潮惨叫久久久| 国产sm重味一区二区三区 | 欧洲熟妇色xxxx欧美老妇| 医院人妻闷声隔着帘子被中出| 成年性午夜无码免费视频| 亚洲性夜色噜噜噜在线观看不卡 | 日本一卡2卡3卡四卡精品网站| 亚洲人成无码网站久久99热国产 | 中国丰满熟妇av| 国产偷国产偷亚洲清高app| 国产色xx群视频射精| 天堂mv在线mv免费mv香蕉| 国产精品毛片在线完整版| 人与嘼av免费| 久久人人爽天天玩人人妻精品| 精品无人区卡一卡二卡三乱码| 亚洲最新版av无码中文字幕| 无码人妻日韩一区日韩二区| 久久久久人妻精品一区三寸蜜桃| 无码人妻精品一区二区蜜桃百度| 成在人线av无码免费高潮水老板| 亚洲人成小说网站色在线观看|