在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MGAT1 Antibody

  • 中文名稱:
    MGAT1兔多克隆抗體
  • 貨號:
    CSB-PA013773ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA013773ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA013773ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MGAT1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    MGAT1; GGNT1; GLCT1; GLYT1; MGAT; Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase protein (156-445AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
  • 基因功能參考文獻:
    1. In this study we showed that the activation of Wnt/beta-catenin pathway culminates in the upregulation of MGAT1 enzyme both at transcriptional and post-transcriptional levels. We also showed that overexpression of the beta-catenin gene (CTNNB1) increased the promoter activity of MGAT1. PMID: 29310626
    2. The presence of the rs4285184 polymorphism of the MGAT1 gene increased the risk for developing body fat associated with obesity in the Mexican population. PMID: 27871764
    3. MGAT1 is downregulated in peripheral blood mononuclear cells of galactosaemia patients. PMID: 26733289
    4. The authors show here that the luminal domain of GnT1IP-L contains its MGAT1 inhibitory activity. PMID: 26371870
    5. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
    6. The IL2RA and IL7RA variants had univariate association in MS and T1D, whereas the MGAT1 and CTLA-4 variants associated with only MS or T1D, respectively. PMID: 24572742
    7. analysis of suppression of cancer progression by MGAT1 shRNA knockdown PMID: 22957033
    8. Genetic variants downstream MGAT1 seem to influence susceptibility to obesity. Moreover, these genetic variants affect the levels of serum unsaturated fatty acids and Delta desaturase indices, variables previously shown to correlate with obesity. PMID: 21304485
    9. Activity of HuGnTI in plants is limited by a combination of reduced protein stability, alternative protein targeting and possibly to some extend to lower enzymatic performance of the catalytic domain in the plant biochemical environment. PMID: 19826906
    10. The analysis enabled us to identify a new candidate gene, MGAT1, associated with weight in women. PMID: 19851299
    11. Findings indicated that cysteine 121 has a structural role in maintaining active site geometry of hGnT1, rather than a catalytic role, and illustrates for the first time the potential utility of E. coli as an expression system for hGnT1. PMID: 17716624

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasm, perinuclear region.
  • 蛋白家族:
    Glycosyltransferase 13 family
  • 數據庫鏈接:

    HGNC: 7044

    OMIM: 160995

    KEGG: hsa:4245

    STRING: 9606.ENSP00000311888

    UniGene: Hs.519818



主站蜘蛛池模板: 日韩人妻无码一区二区三区综合 | 中文天堂最新版资源www官网| 国产高清视频在线观看97| 亚洲国产成人精品无码区一本| 国产乱妇无码大片在线观看| 亚洲日韩精品a∨片无码| а√资源新版在线天堂| 四虎影视在线影院在线观看| 欧美级特黄aaaaaa片| 伊人久久大香线蕉综合影院首页| 免费的av网站手机版| 久久国产精品波多野结衣av| 少妇把腿扒开让我爽爽视频| 午夜影视啪啪免费体验区入口| 国产成人精品午夜视频| 在线亚洲中文精品第1页| 色88久久久久高潮综合影院| 成品人视频ww入口| 2021年国产精品专区丝袜| 超碰97人人做人人爱亚洲尤物| 国产成人精品s8视频| 亚洲精品中文字幕乱码三区| 久久精品亚洲一区二区三区浴池| 天天做天天爱天天要天天| 婷婷伊人久久大香线蕉av| 538在线精品视频| 国产一区二区在线视频| 美女mm131爽爽爽作爱| 中文字幕精品久久久久人妻红杏 | 波多野结av在线无码中文| 国产乱人伦真实精品视频| 一进一出抽搐gif| 亚洲国产婷婷香蕉久久久久久| 影音先锋中文无码一区| 亚洲欧美日韩v在线观看不卡| 国产精品免费看久久久无码| 人妻少妇精品中文字幕av| 亚洲欧美中文日韩在线视频一| 中文字幕日韩人妻不卡一区| 日韩欧美群交p片內射中文| 国语精品一区二区三区|