在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MFAP5 Antibody

  • 中文名稱:
    MFAP5兔多克隆抗體
  • 貨號:
    CSB-PA013750GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    AAT9 antibody; MAGP 2 antibody; MAGP-2 antibody; MAGP2 antibody; MFAP 5 antibody; MFAP-5 antibody; MFAP5 antibody; MFAP5_HUMAN antibody; Microfibril associated glycoprotein 2 antibody; Microfibril-associated glycoprotein 2 antibody; microfibrillar associated protein 5 antibody; Microfibrillar associated protein 5 precursor antibody; Microfibrillar-associated protein 5 antibody; MP25 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Human MFAP5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity. Component of the elastin-associated microfibrils.
  • 基因功能參考文獻:
    1. MFAP5 was up-regulated in breast cancers compared with that in normal breast tissues, and further increased in breast cancer bone metastasis. Functionally, MFAP5 overexpression accelerated breast cancer cell proliferation and migration, while an opposite effect was observed when MFAP5 was knocked down. PMID: 29526753
    2. Study shows that over-expression of MFAP5 and TNNC1 is correlated with cervical lymph node metastasis (CLNM), metastasis relapse-free survival and overall survival. These results propose that MFAP5 and TNNC1 may be potential markers for predicting occult cervical lymphatic metastasis and prognosis of oral tongue carcinoma. PMID: 27713166
    3. Likely pathogenic variants included a TGFB2 variant in one patient and a SMAD3 variant in another. These variants have been reported previously in individuals with similar phenotypes. Variants of uncertain significance of particular interest included novel variants in MYLK and MFAP5, which were identified in a third patient PMID: 26854089
    4. The results answer the question of how MAGP2 controls cell type dependent Notch signaling, but more importantly uncover a new mechanism to understand how extracellular matrices and cellular environments impact Notch signaling. PMID: 26808411
    5. Our results demonstrate that factors involving low-grade inflammation modulate MFAP5 expression and that the modified expression of MFAP5 may further regulate adipose tissue inflammation. PMID: 26054006
    6. FAK/CREB/TNNC1 has a role in mediating the effect of stromal MFAP5 on ovarian cancer metastatic potential PMID: 25277212
    7. Alteration of MAGP-2, a component of microfibrils and elastic fibers, appears as an initiating mechanism of inherited Thoracic aortic aneurysm and dissection (TAAD). PMID: 25434006
    8. EPS led to the discovery of two novel immunomodulatory proteins, MFAP5 and PENK that when administered to mice subjected to endotoxemic shock, reversed the cytokine storm and provided a significant survival benefit PMID: 24496384
    9. Decreased MFAP5 gene expression in the endometrium of patients with implantation failure after in vitro ertilization treatment PMID: 22885067
    10. The MAGP2-based assay provided superior performance for the purpose of cell culture identification compared to assays using standard reference genes. PMID: 20345228
    11. microfibrillar proteins MAGP-1 and MAGP-2 can function outside of their role in elastic fibers to activate a cellular signaling pathway PMID: 16492672
    12. MAGP-2 promotes angiogenic cell spouting in vitro by antagonizing Notch signaling pathways in endothelial cells. PMID: 18417156
    13. Independent evaluation confirmed the association of a prognostic gene microfibril-associated glycoprotein 2 (MAGP2) with poor prognosis in advanced ovarian cancer PMID: 19962670

    顯示更多

    收起更多

  • 相關疾病:
    Aortic aneurysm, familial thoracic 9 (AAT9)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    MFAP family
  • 數據庫鏈接:

    HGNC: 29673

    OMIM: 601103

    KEGG: hsa:8076

    STRING: 9606.ENSP00000352455

    UniGene: Hs.512842



主站蜘蛛池模板: 日日摸日日碰夜夜爽亚洲综合| 亚洲欧美日韩国产手机在线| 精品成人免费一区二区不卡| 亚洲一区av在线观看| 特黄特色的大片观看免费视频| 熟妇熟女乱妇乱女网站| 国产精品亚洲а∨天堂免下载| 国产偷久久久精品专区| 国产精品日本亚洲777| 无码国产成人午夜电影在线观看| 色偷偷888欧美精品久久久| 精品黑人一区二区三区| 国产精品无码2021在线观看| 台湾无码av一区二区三区| 国产日韩在线观看不卡顿| 久久婷婷成人综合色| 午夜性刺激免费看视频| 日本理伦片午夜理伦片| 欧美亚洲另类 丝袜综合网| 亚洲日本乱码中文在线电影 | 亚洲日韩精品欧美一区二区一| 亚洲欧洲日产国码韩国| 西欧free性满足hd| 国产人与禽zoz0性伦多活几年| 在厨房拨开内裤进入毛片| 边吃奶边添下面好爽| 亚洲精品久久av无码一区二区 | 天堂中文а√在线官网| 90后极品粉嫩小泬20p| 国产伦子系列沙发午睡| 成年女人午夜性视频| 精选国产av精选一区二区三区| 久久人人爽天天玩人人妻精品| 曰韩少妇内射免费播放| 欧美人与动人物姣配xxxx| 欧美人禽zozo动人物杂交| 国内大量偷窥精品视频| 国产精品成人a区在线观看| 国产精品国产三级国产an| 蜜臀avwww国产天堂| 日本体内she精高潮|