在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

METTL14 Antibody, Biotin conjugated

  • 中文名稱:
    METTL14兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA884519LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) METTL14 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    KIAA1627 antibody; MET14_HUMAN antibody; Methyltransferase like 14 antibody; Methyltransferase-like protein 14 antibody; METTL14 antibody; N6-adenosine-methyltransferase subunit METTL14 antibody; OTTHUMP00000219837 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation. In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization. M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis. M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells.
  • 基因功能參考文獻:
    1. methyltransferase-like protein 14 in a complex with METTL3 mediates nuclear RNA methylation PMID: 24316715
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    MT-A70-like family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 29330

    OMIM: 616504

    KEGG: hsa:57721

    STRING: 9606.ENSP00000373474

    UniGene: Hs.596872



主站蜘蛛池模板: 自慰系列无码专区| 亚洲欧洲无码一区二区三区| 在线日韩av免费永久观看 | 亚洲国产成人综合一区二区三区 | 色中色成人导航| 无码专区亚洲制服丝袜| 大陆精大陆国产国语精品 | 久久成人网站亚洲综合| 亚洲美女国产精品久久久久久久久| 强制高潮18xxxxhd日韩| 亚洲另类欧美小说图片区| 精品久久久久久亚洲综合网| 裸身美女无遮挡永久免费视频| 亚洲伊人成无码综合影院| 久久熟妇人妻午夜寂寞影院| 日日干夜夜干| 欧洲美女粗暴牲交免费观看| 色噜噜狠狠成人中文综合| 成人av久久一区二区三区| 午夜福利在线永久视频| 日韩成人极品在线内射3p蜜臀| 草的我好爽视频| 欧美成人精品午夜免费影视| 人人爽久久涩噜噜噜av| 国产98在线 | 日韩| 日日噜噜噜噜夜夜爽亚洲精品| 在线播放偷拍一区精品| 精产国品一区二区三产区| 色哟哟网站在线观看| 黑人大荫蒂高潮视频| 久久伊人五月丁香狠狠色| 国产免费又色又爽粗视频| 亚洲国产丝袜精品一区| 国产午夜鲁丝片av无码免费| 少妇人妻挤奶水中文视频毛片| 国色天香网www在线观看| 青青草国产久久精品| 亚洲成色最大综合在线| 火箭视频在线观看精品| 久久先锋男人av资源网站| 亚洲中文字幕无码一久久区 |