在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MEPE Antibody

  • 中文名稱:
    MEPE兔多克隆抗體
  • 貨號:
    CSB-PA013704GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Matrix extracellular phosphoglycoprotein antibody; MEPE antibody; MEPE_HUMAN antibody; OF45 antibody; Osteoblast/osteocyte factor 45 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Human MEPE
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Promotes renal phosphate excretion and inhibits intestinal phosphate absorption. Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes. Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage. Promotes dental pulp stem cell proliferation and differentiation.
  • 基因功能參考文獻:
    1. Results indicate an association of MEPE gene inactivation with decreased survival after DNA damage. PMID: 23570370
    2. Mice deficient in an ortholog of MEPE show increased bone mass and are resistant to aging-related bone loss. PMID: 12421822
    3. results indicated that MEPE appeared to play an important positive role in proliferation and osteogenesis differentiation of DPCs through interaction with downstream signals. PMID: 22341070
    4. MEPE or the MEPE-derived acidic serine aspartate-rich MEPE-associated motif peptide may contribute to decreased bone mineralization in Oncogenic osteomalacia patients. PMID: 21739089
    5. Among migraineurs with aura rs7698623 in MEPE (OR = 6.37; 95% CI 3.15-12.90; p = 2.7x10(-7)) and rs4975709 in IRX4 (OR = 5.06; 95% CI 2.66-9.62; p = 7.7x10(-7)) appeared to be associated with ischemic stroke. PMID: 21779381
    6. Sclerostin acts through regulation of the PHEX/MEPE axis at the preosteocyte stage and serves as a master regulator of physiologic bone mineralization. PMID: 21312267
    7. MEPE may play a regulatory role in periodontal ligament cell osteogenic differentiation. PMID: 19031789
    8. These results suggest that abnormal MEPE cleavage occurs when PHEX activity is deficient in humans. PMID: 20581062
    9. This study demonstrates the importance of posttranslational modification for the site-specific activity of MEPE and its ASARM peptide. PMID: 19998030
    10. The patterns of expression of FGF-23, MEPE, and DMP1 differ markedly in trabecular bone, suggesting that individual osteocytes may have specialized functions. PMID: 19679205
    11. MEPE/OF45, a new dentin/bone matrix protein and candidate gene for dentin diseases mapping to chromosome 4q21. Expressed during odontogenesis. PMID: 12489176
    12. There is evidence for a hormone/enzyme/extracellular matrix protein cascade involving fibroblastic growth factor 23 (FGF23), a phosphate-regulating gene with homologies to (PHEX) and (MEPE)--REVIEW PMID: 12791601
    13. MEPE is predominantly expressed by osteocytes in human bone, with significant expression by osteocytes within mineralized bone PMID: 15108058
    14. The results are consistent with MEPE being involved in phosphate and bone metabolism in a normal population. PMID: 15292364
    15. MEPE expression is higher when cells proliferate, whereas it is downregulated as cells differentiated PMID: 18547474
    16. MEPE is a candidate phosphatonin involved in phosphate homeostasis, acting in both the kidney and the gastrointestinal tract PMID: 19005008
    17. MEPE is expressed in salivary gland ducts. PMID: 15329369
    18. MEPE is expressed on the luminal surface of kidney proximal tubules. PMID: 15954904

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性:
    Expressed by osteoblasts. Expressed by stem cells in dental pulp. Expressed by mesenchymal cells in dental papilla and dental pulp. Expressed in teeth, specifically in decidious dentin. Expressed in ondotoblasts. Expressed in salivary glands. Secreted fro
  • 數據庫鏈接:

    HGNC: 13361

    OMIM: 605912

    KEGG: hsa:56955

    STRING: 9606.ENSP00000354341

    UniGene: Hs.676357



主站蜘蛛池模板: 日韩免费特黄一二三区| 日产乱码一区二区三区在线| 麻豆tv入口在线看| 日本在线看片免费人成视频| 亚洲免费网站观看视频| 无码专区丰满人妻斩六十路| 免费看一区二区三区四区| 国产精品无码专区| 国模无码一区二区三区| 国产熟女精品视频大全| 亚洲一区天堂九一| 久久久久久夜精品精品免费啦 | 丰满少妇被猛烈进入试看| 久久综合狠狠综合久久综合88| 青草青草久热精品视频在线观看| 永久免费观看美女裸体的网站| 欧洲无码精品a码无人区| 最新亚洲一卡二卡三卡四卡| 亚洲综合av一区二区三区| 麻豆一区二区三区精品视频| 少妇挑战黑人高潮惨叫| 性男女做视频观看网站| 天堂最新版在线www官网中文地址| 在线观看人成视频免费| 日本乱妇乱子视频网站-百度| 亚洲2021av天堂手机版| 国产精品久久人妻互换| 日韩人妻无码免费视频一区二区三区| 男女性色大片免费网站| 亚洲国产天堂久久综合| 日本国产网曝视频在线观看| 亚洲中文无码mv| 亚洲 a v无 码免 费 成 人 a v | 暖暖视频 免费 日本社区| 国产精品人妻在线观看| 亚洲一区二区三区偷拍女厕| 成年轻人电影www无码| 欧美成妇人吹潮在线播放| 在线永久无码不卡av| 欧美一区二区三区| 波多野结衣一区二区三区高清av|