在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MED28 Antibody, HRP conjugated

MED28 Antibody, HRP conjugated

  • 中文名稱：
    MED28兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA863955LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MED28 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MED28
  • 別名：
    EG1 antibody; Endothelial-derived protein 1 antibody; FKSG20 antibody; Magicin antibody; med28 antibody; MED28_HUMAN antibody; Mediator complex subunit 28 antibody; Mediator of RNA polymerase II transcription subunit 28 antibody; Merlin and Grb2-interacting cytoskeletal protein antibody; Tumor angiogenesis marker EG-1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Mediator of RNA polymerase II transcription subunit 28 protein (1-178AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
  • 基因功能參考文獻(xiàn)：
    1. MED28 modulates the development of epithelial-mesenchymal transition through NFkappaB in human breast cancer cells. PMID: 27662245
    2. All trans-retinoic acid can reverse the suppressive effect of MED28 on HBP1 and E-cadherin and inactivate the Wnt/beta-catenin pathway in colorectal cancer, suggesting a protective effect of ATRA against colorectal cancer. PMID: 26660958
    3. This paper describes a link between Med23 and IFN-lambda3, provides evidence for the crucial role of IFN-lambda in HSV-1 immune control. PMID: 23950709
    4. These data indicate that MED28 regulates cellular migration in a MEK1-dependent manner in human breast cancer cells, reinforcing the important cellular roles of MED28. PMID: 22495818
    5. High MED28 is associated with breast cancer. PMID: 20584319
    6. demonstrate an interaction between Grb2 and magicin. In addition, merlin is capable of forming a ternary complex with magicin and Grb2 PMID: 15467741
    7. EG-1 is a positive stimulator of cellular proliferation, and may possibly be involved in signaling pathways involving Src and MAPK activation. PMID: 16024617
    8. May serve as a multi-faceted adaptor/scaffold to relay cellular signaling to the cytoskeleton and from the cytoskeleton to the nucleus. PMID: 16899217
    9. EG-1 may be involved in signaling pathways including c-Src activation. PMID: 16964398
    10. EG-1 has a role in breast tumor growth PMID: 17568184
    11. Study reports that down-regulation of human Med28 expression in NIH3T3 cells results in a significant induction of several genes associated with smooth muscle cell (SMC)differentiation; conversely, overexpression of MED28 represses SMC gene expression. PMID: 17848560

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm. Membrane; Peripheral membrane protein. Note=According to PubMed:15467741, it is cytoplasmic and mainly membrane-associated.
  • 蛋白家族：
    Mediator complex subunit 28 family
  • 組織特異性：
    Widely expressed. Highly expressed in vascular tissues such as placenta, testis and liver.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24628

    OMIM: 610311

    KEGG: hsa:80306

    STRING: 9606.ENSP00000237380

    UniGene: Hs.731966



主站蜘蛛池模板： 国产午夜精品一区二区| 亚洲欧美日韩国产国产a| 国产精品免费大片| 精品国产乱码久久久久夜深人妻| 亚洲 日韩 国产 中文有码| 亚洲日韩欧美国产另类综合| 伊人av超碰伊人久久久| 好了av四色综合无码| 国产精品成人久久久久久久| 亚洲国产精品日本无码网站| 99久久国产综合精品五月天| 免费国精产品wnw2544| 欧美人与禽zoz0性伦交| 久久婷婷六月综合色液啪| 韩国主播av福利一区二区| 亚洲a∨无码无在线观看| 国产女人高潮视频在线观看| 国产超碰人人做人人爽av动图| 人人添人人澡人人澡人人人人 | 中文字幕人妻丝袜成熟乱| 久久久久人妻精品一区三寸蜜桃| 国产农村乱对白刺激视频| 夜晚被公侵犯的人妻深田字幕| 国产av无码专区影视| 亚洲 欧美 国产 日韩 中文字幕| 亚洲精品一区二区久久| 精品亚洲国产成av人片传媒| 婷婷四虎东京热无码群交双飞视频| 天堂а√在线地址8| 国产免费无遮挡吸奶头视频| 大桥未久亚洲一区二区| 国产欧美丝袜在线二区| 久久人人爽人人爽人人片av不| 国产无线乱码一区二三区| 涩里番网污站| 国产成人精品a视频免费福利| 无码人妻少妇伦在线电影| 免费毛片a线观看| 久久理论片午夜琪琪电影院| 大伊香蕉精品一区视频在线| 久久精品国产曰本波多野结衣|