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MED20 Antibody, Biotin conjugated

  • 中文名稱:
    MED20兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA862046LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MED20 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MED20
  • 別名:
    MED20 antibody; TRFP antibody; Mediator of RNA polymerase II transcription subunit 20 antibody; Mediator complex subunit 20 antibody; TRF-proximal protein homolog antibody; hTRFP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Mediator of RNA polymerase II transcription subunit 20 protein (1-212AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能參考文獻:
    1. Our analyses revealed no apparent differences in protein expression profiles of SRBs in central and peripheral regions of human donor tissues, indicating that carotenoid-binding proteins rather than transporters are likely to mediate selective accumulation of carotenoids into the macula. PMID: 28947101
    2. We identified the first and homozygous mutation (p.Gly114Ala) in the Mediator subunit 20 gene (MED20) in siblings presenting with infantile-onset spasticity and childhood-onset dystonia, progressive basal ganglia degeneration, and brain atrophy PMID: 25446406
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Mediator complex subunit 20 family
  • 數據庫鏈接:

    HGNC: 16840

    OMIM: 612915

    KEGG: hsa:9477

    STRING: 9606.ENSP00000265350

    UniGene: Hs.278434



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