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MED18 Antibody

  • 中文名稱:
    MED18兔多克隆抗體
  • 貨號:
    CSB-PA995695
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA995695(MED18 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cell, Primary antibody: CSB-PA995695(MED18 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    MED18
  • 別名:
    FLJ20045 antibody; hMED 18 antibody; hMED18 antibody; Human Mediator of RNA Polymerase II Transcription antibody; MED 18 antibody; med18 antibody; MED18_HUMAN antibody; Mediator complex subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 antibody; Mediator of RNA polymerase II transcription subunit 18 homolog antibody; OTTHUMP00000003645 antibody; p28b antibody; TRAP/mediator complex subunit p28b antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Full length fusion protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • 基因功能參考文獻(xiàn):
    1. A novel transcriptional repression mechanism of hMED18 mediated by hCDK8 and further a novel positive role of free CDK/cyclin module in transcriptional activation is described. PMID: 24840924
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Mediator complex subunit 18 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 25944

    OMIM: 612384

    KEGG: hsa:54797

    STRING: 9606.ENSP00000362948

    UniGene: Hs.479911



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