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ME3 Antibody

  • 中文名稱：
    ME3兔多克隆抗體
  • 貨號：
    CSB-PA006739
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of RAW264.7 cells using ME3 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ME3
  • 別名：
    ME3NADP-dependent malic enzyme antibody; mitochondrial antibody; NADP-ME antibody; EC 1.1.1.40 antibody; Malic enzyme 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ME3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. ATP inhibition is proposed to be determined by the electrostatic potential involving the positive charge on the side chain of Lys346 PMID: 18959763
    2. Studies demonstrate that the Lys57 residue plays dual functional roles in the structural integrity of the allosteric site and in the subunit-subunit interaction at the dimer interface of m-NAD(P)-ME. PMID: 19236308
    3. human c-NADP-ME exists mainly as a tetramer, whereas human m-NAD(P)-ME exists as a mixture of dimers and tetramers PMID: 19416979
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Malic enzymes family
  • 組織特異性：
    Expressed predominantly in organs with a low-division rate.
  • 數據庫鏈接：

    HGNC: 6985

    OMIM: 604626

    KEGG: hsa:10873

    STRING: 9606.ENSP00000352657

    UniGene: Hs.199743



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