在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MC5R Antibody

MC5R Antibody

  • 中文名稱：
    MC5R兔多克隆抗體
  • 貨號：
    CSB-PA003205
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 3T3 cells using MC5-R Polyclonal Antibody
    • Western Blot analysis of NIH-3T3 cells using MC5-R Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    MC5R; Melanocortin receptor 5; MC5-R; MC-2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human MC5-R.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
  • 基因功能參考文獻：
    1. Mutations in residues S4/S5 and S17/E18 retained MC5R at the ER/Golgi complex and did not affect MC5R homodimerization. PMID: 28396017
    2. D115 and D119 in TM3, F195 in TM5, and F254 in TM6 may form a binding pocket for NDP-alpha-MSH binding. PMID: 23414113
    3. Melanocortin 5 receptor signaling and internalization: role of MAPK/ERK pathway and beta-arrestins 1/2. PMID: 22871966
    4. Variations in the melanocortin 5 receptor gene are unlikely to confer susceptibility to bipolar disorder in this sample. PMID: 16314755
    5. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119 were made at MC5R. PMID: 17482720
    6. MC5R signals through a PI3K-regulated Akt-independent pathway leading to downstream activation of ERK1/2 PMID: 19428994

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed in the brain but not in the melanoma cells.
  • 數據庫鏈接：

    HGNC: 6933

    OMIM: 600042

    KEGG: hsa:4161

    STRING: 9606.ENSP00000318077

    UniGene: Hs.248145



主站蜘蛛池模板： 西西人体大胆瓣开下部毛茸茸 | 亚洲人午夜射精精品日韩| 老色鬼永久视频网站| 国产精品自在线拍亚洲另类| 欧美最猛黑人xxxxx猛交| 内射老妇bbwx0c0ck| 伊人久久成综合久久影院| 日韩欧美亚洲综合久久影院ds| 男女下面一进一出无遮挡| 成人性做爰片免费视频| 大香伊蕉在人线国产网站首页| 久久婷婷色综合老司机| 伊人亚洲大杳蕉色无码| 九一九色国产| 欧美亚洲国产精品久久| 最近最好的中文字幕2019免费| 亚洲人成色777777老人头| 香港三级韩国三级日本三级| 国产精品尹人在线观看| 樱花草在线社区www中国| 成人免费无码av| 无码熟妇人妻av在线影片最多| 欧美人与动牲交欧美精品| 奶头又大又白喷奶水av| 亚洲精品乱码久久久久久不卡| 日本中文一二区有码在线| 成人无码a∨电影免费| 乱人伦中文字幕成人网站在线| 男人女人午夜视频免费| 日韩免费无码视频一区二区三区| 国产午夜精品久久久久免费视| 午夜射精日本三级| 色婷婷我要去我去也| 伊人久久大香线蕉影院| 亚洲综合无码一区二区| 中文在线www天堂网| 天天做天天爱夜夜夜爽毛片| 3p人妻少妇对白精彩视频| 天堂va视频一区二区| 欧美内射深喉中文字幕| 大陆熟妇丰满多毛xxxⅹ|