在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MAZ Antibody, Biotin conjugated

MAZ Antibody, Biotin conjugated

  • 中文名稱：
    MAZ兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA013528LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MAZ Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAZ
  • 別名：
    MAZ antibody; MAZ_HUMAN antibody; MAZI antibody; MYC associated zinc finger protein antibody; Myc-associated zinc finger protein antibody; Pur-1 antibody; Pur1 antibody; Purine binding transcription factor antibody; Purine-binding transcription factor antibody; SAF 1 antibody; SAF 2 antibody; SAF-1 antibody; SAF-2 antibody; SAF-3 antibody; Serum amyloid A activating factor 1 antibody; Serum amyloid A activating factor 2 antibody; Transcription factor Zif87 antibody; ZF87 antibody; Zif87 antibody; Zinc finger protein 801 antibody; Zinc finger protein, 87 kilodaltons antibody; ZNF801 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Myc-associated zinc finger protein (30-80AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional regulator, potentially with dual roles in transcription initiation and termination.; Binds DNA and functions as a transcriptional activator. Binds to two G/A-rich sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.; Binds DNA and functions as a transcriptional activator. Inhibits MAZ isoform 1-mediated transcription.; Binds DNA and functions as a transcriptional activator.
  • 基因功能參考文獻：
    1. MAZ can promote the invasion and metastasis of hepatocellular carcinoma by inducing epithelial-mesenchymal transition (EMT). PMID: 27861158
    2. A quantitative association between MAZ-autoantibody optical density on ELISA and the cumulative inflammatory burden of atherosclerosis on (18)F-FDG PET/CT could be shown, suggesting MAZ-Ab as potential biomarker for atherosclerotic disease. PMID: 28279832
    3. The data indicate that MAZ is essential to bypass MYB promoter repression by RB family members and to induce MYB expression. PMID: 28973440
    4. MAZ/FOXF2 axis can promote the proliferation of basal like breast cancer cells and suppress disease progression. PMID: 28577976
    5. Data suggest that long noncoding RNA PlncRNA1 and microRNA miR-34c bound together to regulate the expressions of MAZ, ZO-1 and occludin. PMID: 28153728
    6. a transcriptional factor, Myc-associated zinc finger protein (MAZ), plays an important role in ADAM10 transcription in response to CT-1 in neural stem/progenitor cells. PMID: 26867947
    7. Akt phosphorylates MAZ at Thr385, and the phosphorylated MAZ is released from the p53 promoter, leading to transcriptional activation of p53. PMID: 26902421
    8. Myc-associated zinc-finger protein (MAZ) was identified as a direct target of miR-449a, mediating the tumor-suppressive effects. PMID: 25487955
    9. Studies show a feed-forward regulatory pathway in breast cancer cells where SAF-1 acts as a transcriptional inducer of Ras which in turn increases DNA-binding and transcriptional activities of SAF-1 which in turn, increases transcription of Ras. PMID: 25449683
    10. In conclusion, our present study indicated that miR-34c regulated the permeability of BTB via MAZ-mediated expression changes of ZO-1, occludin, and claudin-5. PMID: 25201524
    11. Role of MAZ in prostate cancer and its interaction with androgen receptor were investigated. siRNA knockdown of AR significantly decreased MAZ expression, and knockdown of MAZ significantly increased the expression of AR. PMID: 23609189
    12. these findings reveal that SAF-1 is a hitherto unrecognized participant in inducing VEGF expression in triple-negative breast cancer cells, an aggressive form of breast cancer that currently lacks effective treatment options. PMID: 21665940
    13. relative abundance of SAF-2 plays a critical role in the fine tuned regulation of inflammation-responsive genes that are controlled by SAF-1 PMID: 12270922
    14. epitope spreading between the Tr antigen and the MAZ-DCC complex offers a possible model of immune-mediated cerebellar disease. PMID: 12509857
    15. A novel promoter element was detected in the human MMP1 gene, and the inflammation-responsive transcription factor SAF-1 was found to interact with it in osteoarthritis PMID: 12528113
    16. The putative -45 to -39 MYC-associated zinc finger protein-binding site regulates the constitutive activity of human PTHR1 P2 promoter. PMID: 14765995
    17. SAF-1 controls cell cycle progression via p21 induction, and pathophysiological conditions that favor overexpression of SAF-1, such as an acute inflammatory condition, can trigger cellular growth arrest. PMID: 15067082
    18. SAF-1 transcription factor is a regulator of MMP-14 gene induction in monocyte/macrophage cells. PMID: 15528467
    19. The MAZ pause element promotes Pol II termination downstream of a poly(A) signal and the strength of the poly(A) signal. PMID: 16648491
    20. In transgenic mice SAF-1 plays a key role in the development of reactive amyloid A amyloidosis, a consequence of chronic inflammation. PMID: 16888022
    21. SAF-1 induces VEGF transcription by directly binding to its promoter; markedly higher levels of SAF-1 interaction with the VEGF promoter was detected in the cartilage tissues of arthritic mice as well as human osteoarthritic patients. PMID: 17237427
    22. These findings help to define the molecular mechanism driving the high expression of PPARgamma1 in breast cancer and raise new questions regarding the role of MAZ in cancer progression. PMID: 17902047
    23. MAZ and Sp1 play important roles on the transcriptional activation of the human edn promoter through specific binding to a 34-nt segment present in representative primate eosinophil rnase promoters. PMID: 17927842
    24. Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1. PMID: 19074642
    25. Existence of multiple promoters regulation MAZ, which is expressed during inflammation. PMID: 19583771

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Note=In brains of Alzheimer disease patients, present in a plaque-like structures.
  • 組織特異性：
    Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).; [Isoform 1]: Expressed in the heart, brain, placenta, lung, liver, skeletal muscle and weakly expressed in the kidney. Ex
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6914

    OMIM: 600999

    KEGG: hsa:4150

    STRING: 9606.ENSP00000219782

    UniGene: Hs.23650



主站蜘蛛池模板： 妖精色av无码国产在线看| 2018年秋霞无码片| 亚洲欧美成αⅴ人在线观看| 久久精品国产精品亚洲蜜月| 清纯小美女主播流白浆| 国产精品久久久久久久久久久久人四虎 | 少妇被躁爽到高潮无码久久 | 久久久亚洲色| 人妻护士在线波多野结衣| 亚洲综合欧美制服丝袜| 中文无码人妻影音先锋| 中国丰满人妻videoshd| 久久综合色之久久综合| 欧洲免费无线码在线一区 | 真实国产乱啪福利露脸| 久久久久久久久久久国产| www亚洲精品久久久| 日本高清va在线播放| 顶级欧美做受xxx000| 嫩草av久久伊人妇女超级a| 国产精品久久国产三级国| 久久久精品区二区三区免费| 最新亚洲伦理中文字幕| 在线黑人抽搐潮喷| 丁香啪啪综合成人亚洲| 日本欧美久久久久免费播放网| 青青草无码伊人久久| 国产av偷闻女邻居内裤被发现| 中文字幕被公侵犯的漂亮人妻| 日韩av无码中文字幕| 99热这里只有精品最新地址获取| 欧美亚洲另类丝袜综合网| 久久大香国产成人av| 3d动漫精品啪啪一区二区下载 | 天堂亚洲国产中文在线| 国产三级做爰在线播放| 精品一区二区不卡无码av| 欧美亚洲日本国产综合在线 | 日本熟妇乱子伦xxxx| 亚洲国产成人久久综合一区| 国产亚洲欧美另类一区二区|