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MATN2 Antibody, HRP conjugated

  • 中文名稱:
    MATN2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA013521LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MATN2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MATN2
  • 別名:
    Crtm2 antibody; MATN 2 antibody; Matn2 antibody; MATN2_HUMAN antibody; Matrilin-2 antibody; Matrilin2 antibody; MGC102477 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Matrilin-2 protein (746-867AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in matrix assembly.
  • 基因功能參考文獻:
    1. findings showed that YopK binds to the cell surface-exposed endogenous MATN2 and that purified YopK protein strongly inhibits the bacterial adherence to HeLa cells PMID: 28533472
    2. Data show that the mRNA and protein levels of matrilin-2 were increased after irradiation treatment in both mouse lung tissue and human pulmonary alveolar epithelial cells (HPAEpiC). PMID: 27923659
    3. Taken together, our results showed that high-glucose-induced Matrilin-2 expression that was mediated by the TGF-beta1/Smad3 signaling pathway might play a role in Diabetic nephropathy (DN) pathogenesis and our finding provided a potential diagnostic and/or therapeutic target for DN. PMID: 27105914
    4. Matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal, partly through a TLR4-mediated mechanism PMID: 26271809
    5. matrilin-2, a filament-forming protein widely distributed in extracellular matrices. PMID: 11852232
    6. matrilin-2 is expressed in normal skin by keratinocytes and fibroblasts and may thus contribute to cutaneous homeostasis. PMID: 12164922
    7. study of interactions by which matrilin-2 can be integrated into extracellular filamentous networks PMID: 12180907
    8. These results suggest that matrilin-2 may be a specific and clinically useful biomarker for discriminating between indolent and clinically aggressive pilocytic astrocytoma. PMID: 16401863
    9. DeltaNp63/BMP-7 signaling pathway modulates wound healing process through the regulation of matrilin-2. PMID: 18328806
    10. data indicate matrilin-2 is a novel basement membrane component in the liver, synthesized during sinusoidal "capillarization" in cirrhosis & in hepatocellular carcinoma PMID: 18386166

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  • 亞細胞定位:
    Secreted.
  • 數據庫鏈接:

    HGNC: 6908

    OMIM: 602108

    KEGG: hsa:4147

    STRING: 9606.ENSP00000430487

    UniGene: Hs.189445



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