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MATN1 Antibody

  • 中文名稱:
    MATN1兔多克隆抗體
  • 貨號:
    CSB-PA602770
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA602770(MATN1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA602770(MATN1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    MATN1
  • 別名:
    Cartilage matrix protein antibody; CMP antibody; CRTM antibody; Matn1 antibody; MATN1_HUMAN antibody; Matrilin 1 antibody; Matrilin 1 cartilage matrix protein antibody; Matrilin-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human MATN1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.
  • 基因功能參考文獻:
    1. polymorphisms associated with mandibular retrognathism PMID: 29407503
    2. Matrilin-1 is an inhibitor of neovascularization PMID: 24692560
    3. this meta-analysis found an overall significant association of rs1149048 polymorphism with risk of AIS, especially in Asian population. PMID: 24469715
    4. The A allele of single nucleotide polymorphism rs1065755 in the MATN1 gene is associated with adolescent idiopathic scoliosis. PMID: 22193623
    5. we concluded that MATN1 SNP is not associated with either adolescent idiopathic scoliosis predisposition or curve severity in Japanese. PMID: 21308753
    6. There is an association between matrilin-1 levels and curve progression in adolescent idiopathic scoliosis. PMID: 20137399
    7. Genotype GG of matrilin-1 gene is indicative of less bracing effectiveness in adolescent idiopathic scoliosis. PMID: 20137728
    8. Matrilin-1 A-domains have a role in cartilage ECM assembly PMID: 20729554
    9. Genotyping results showed Matrilin-1 polymorphism haplotype TGC (ht4; 158T, 7987G, and 8572C alleles) had pronounced risk effect for mandibular prognathism compared with controls. PMID: 20739701
    10. The tagSNP rs1149048 polymorphism in the MATN1 promoter region is associated with both susceptibility and disease severity in adolescent idiopathic scoliosis. PMID: 20092731
    11. Pseudoachondroplasia is associated with mutations in the cartilage oligomatrix protein gene. PMID: 15552564
    12. the tagSNP rs1149048 polymorphism in the MATN1 promoter region was associated with both susceptibility and disease progression in adolescent idiopathic scoliosis . PMID: 18985072

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  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 數據庫鏈接:

    HGNC: 6907

    OMIM: 115437

    KEGG: hsa:4146

    STRING: 9606.ENSP00000362870

    UniGene: Hs.150366



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