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  4. MAST2 Antibody

MAST2 Antibody

  • 中文名稱：
    MAST2兔多克隆抗體
  • 貨號：
    CSB-PA003196
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 293 cells using MAST205 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MAST2
  • 別名：
    EC 2.7.11.1 3 antibody; FLJ39200 antibody; KIAA0807 antibody; MAST 2 antibody; MAST 205 antibody; Mast2 antibody; MAST2_HUMAN antibody; Microtubule associated serine/threonine kinase 2 antibody; Microtubule associated testis specific serine/threonine protein kinase antibody; Microtubule-associated serine/threonine-protein kinase 2 antibody; MTSSK antibody; OTTHUMP00000009697 2 antibody; OTTHUMP00000046616 antibody; RP4 533D7.1 antibody; RP4-533D7.1 2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MAST205.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.
  • 基因功能參考文獻：
    1. we observed 3 case-specific duplications of the autosomal gene MAST2, and in a replication phase we found another 11 duplications PMID: 26203179
    2. Viral and PTEN peptide interactions to MAST2-PDZ occur via a unique kinetic step which involves both canonical C-terminal PBM binding and N-terminal anchoring. PMID: 25942057
    3. MAST2 gene rearrangements occur in invasive breast carcinoma. PMID: 24140425
    4. MAST205 plays an important role in regulating CFTR expression and function PMID: 23504457
    5. The MAST2 sequence at the 5' end of SVA(F1) acts as a positive transcriptional regulator in human germ cells. PMID: 22609064
    6. Recruitment of a MAST2 CpG island was most likely beneficial to the hybrid retrotransposons because it could significantly increase retrotransposition frequency. PMID: 19961423
    7. Studies report the identification of a new subfamily of SVA, which apparently formed after an alternative splicing event where the first exon of the MAST2 gene spliced into an intronic SVA and subsequently retrotransposed. PMID: 19635844

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  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the sub-membranous area on interaction with CDHR2.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 組織特異性：
    Abundant in the testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19035

    OMIM: 612257

    KEGG: hsa:23139

    STRING: 9606.ENSP00000354671

    UniGene: Hs.319481



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