在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MARVELD1 Antibody

MARVELD1 Antibody

  • 中文名稱：
    MARVELD1兔多克隆抗體
  • 貨號：
    CSB-PA106910
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA106910(MARVELD1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA106910(MARVELD1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA106910(MARVELD1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MARVELD1
  • 別名：
    MARVELD1; MRVLDC1; MARVEL domain-containing protein 1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human MARVELD1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration.
  • 基因功能參考文獻：
    1. MARVELD1 substantially inhibits nonsense-mediated RNA decay by decreasing the pioneer round of translation but not steady-state translation, and is an important component of the molecular machinery containing UPF1 and Y14. MARVELD1 promotes the dissociation of SMG1 from UPF1, resulting in the repression of serine phosphorylation of UPF1, and subsequently blocks the recruitment of SMG5. PMID: 23826386
    2. Study demonstrates that MARVELD1-mediated balance of integrin beta1 and beta4 regulates cell surface ultrastructure and epithelial-mesenchymal transition phenotype of non-small cell lung cancer (NSCLC). PMID: 26509557
    3. MARVELD1 silencing is an appealing diagnostic biomarker for lung cancer. PMID: 25520033
    4. Importin-beta1 mediates the non-classical nucleocytoplasmic transport of MARVELD1. PMID: 26107903
    5. MARVELD1 plays a role in pre-mRNA processing of integrin beta1. PMID: 24055813
    6. Our findings suggest that MARVELD1 is a tumor suppressor by negatively regulating proliferation, tumor growth and chemosensitivity of HCC cells via increasing p53 and p16 in vitro and in vivo. PMID: 22320884
    7. MARVELD1 protein is located in nucleus instead of cell membrane in several different tumors, in males and in females. PMID: 19364627

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus.
  • 組織特異性：
    Widely expressed in normal tissues. Down-regulated in multiple primary tumors.
  • 數據庫鏈接：

    HGNC: 28674

    KEGG: hsa:83742

    STRING: 9606.ENSP00000441365

    UniGene: Hs.744073



主站蜘蛛池模板： 亚洲色欲色欲综合网站| 无码国产成人午夜视频在线播放| 成人av在线一区二区三区| 东京热人妻丝袜无码av一二三区观 | 久久婷婷五月综合色奶水99啪| 午夜成人理论无码电影在线播放| 亚洲欧美日韩国产成人精品影院| 久久综合九色综合97网| 亚洲一区二区无码影院| 开心婷婷五月激情综合社区| 成熟了的熟妇毛茸茸| 国产乱人伦av在线a更新| 午夜人性色福利无码视频在线观看| 精品亚洲欧美无人区乱码| 成人片黄网站色大片免费| 午夜男女无遮挡拍拍视频| 蜜桃麻豆www久久国产sex| 水蜜桃亚洲一二三四在线| 中文字幕精品无码一区二区三区| 8ⅹ8x擦拨擦拨成人免费视频| 精品丝袜国产自在线拍小草| 亚洲色欧美色2019在线| 中文无码精品a∨在线观看不卡 | av无码东京热亚洲男人的天堂| 日本一卡2卡3卡4卡5卡精品视频| 欧美日本免费一区二区三区| 亚洲第一se情网站| 女性自慰网站免费看ww| 欧洲免费一区二区三区视频| 一本大道无码人妻精品专区| 久久久国产成人一区二区| 日本欧美大码aⅴ在线播放| 亚洲欧美综合区自拍另类| 人妻丰满熟妇av无码区不卡| 欧美人成视频在线视频 | 国产69精品久久久久人妻| 日本在线看片免费人成视频1000| 国产免费人成在线视频app| 国产免费一区二区三区在线观看| 99这里只有精品| 国产成人av国语在线观看|