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  4. MAP9 Antibody

MAP9 Antibody

  • 中文名稱：
    MAP9兔多克隆抗體
  • 貨號：
    CSB-PA060167
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MAP9
  • 別名：
    ASAP antibody; Aster associated protein antibody; Aster-associated protein antibody; Map9 antibody; MAP9_HUMAN antibody; microtubule associated protein 9 antibody; Microtubule-associated protein 9 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MAP-9.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
  • 基因功能參考文獻：
    1. MAP9 downregulation is associated with colorectal malignancy. PMID: 24876664
    2. ASAP stabilizes p53 both by alleviating MDM2-mediated p53 ubiquitination and by enhancing its p300-dependent acetylation. PMID: 22672907
    3. Results highlight dual ASAP regulation by Plk1 and further confirm the importance of ASAP for spindle pole organization, bipolar spindle assembly, and mitosis. PMID: 20615875
    4. ASAP is a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. PMID: 16049101
    5. Study demonstrates that AurA-mediated phosphorylation of ASAP is essential to spindle formation and mitosis. PMID: 17925329

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  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
  • 數據庫鏈接：

    HGNC: 26118

    OMIM: 610070

    KEGG: hsa:79884

    STRING: 9606.ENSP00000310593

    UniGene: Hs.61271



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