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  4. MAP4K5 Antibody

MAP4K5 Antibody

  • 中文名稱：
    MAP4K5兔多克隆抗體
  • 貨號(hào)：
    CSB-PA286198
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA286198(MAP4K5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA286198(MAP4K5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MAP4K5
  • 別名：
    MAP4K5 antibody; Mitogen-activated protein kinase kinase kinase kinase 5 antibody; EC 2.7.11.1 antibody; Kinase homologous to SPS1/STE20 antibody; KHS antibody; MAPK/ERK kinase kinase kinase 5 antibody; MEK kinase kinase 5 antibody; MEKKK 5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human MAP4K5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:15-1:50
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
  • 基因功能參考文獻(xiàn)：
    1. MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma. PMID: 27023625
    2. TNF signaling leads to oligomerization, ubiquitination, and activation of GCKR and activation of the SAPK pathway in a manner that depends upon TRAF2 polyubiquitination and oligomerization and Ubc13 function PMID: 12591926
    3. The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai. PMID: 16699725
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  • 組織特異性：
    Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6867

    OMIM: 604923

    KEGG: hsa:11183

    STRING: 9606.ENSP00000013125

    UniGene: Hs.130491



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