在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MAGT1 Antibody

  • 中文名稱:
    MAGT1兔多克隆抗體
  • 貨號:
    CSB-PA013368GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    MAGT1
  • 別名:
    MAGT1; IAG2; PSEC0084; UNQ628/PRO1244; Magnesium transporter protein 1; MagT1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1; Oligosaccharyl transferase subunit MAGT1; Implantation-associated protein; IAP
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MAGT1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues; in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.; May be involved in Mg(2+) transport in epithelial cells.
  • 基因功能參考文獻:
    1. evaluation of MAGT1 and AKAP13 expression in clinical hepatocellular carcinoma tissues by immunohistochemistry suggested that both proteins were strongly expressed in tumor tissues with significantly higher average immunoreactive scores of Remmele and Stegner (IRS) than in non-tumor tissues PMID: 26617690
    2. A 0.8 kb intronic duplication in MAGT1 and a single base pair deletion in the last exon of ATRX were identified in a family with five males demonstrating intellectual disability (ID) and unusual skin findings (e.g., generalized pruritus). PMID: 24130152
    3. A deficiency in magnesium transporter 1 (MAGT1), an Mg(2+)-specific transporter, leads to the absence of a T cell antigen receptor-stimulated Mg(2+)flux and an attenuation of T cell activation. PMID: 21983175
    4. identifed a novel gene that encodes a protein involved with Mg2+-evoked transport, MagT1; results suggest that MagT1 may provide a selective and regulated pathway for Mg2+ transport in epithelial cells[MagT1] PMID: 15804357
    5. study shows that mutations in two OTase-subunit genes, N33/TUSC3 and IAP result in autosomal-recessive nonsyndromic mental retardation PMID: 18455129
    6. MagT1 is universally expressed in all tissues and its expression level is up-regulated in low extracellular Mg(2+). Knockdown of either MagT1 or TUSC3 protein significantly lowers the total and free intracellular Mg(2+) concentrations in cell lines. PMID: 19717468

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia (XMEN)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    OST3/OST6 family
  • 組織特異性:
    Ubiquitous. Expressed at very low levels in brain, lung and kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 28880

    OMIM: 300715

    KEGG: hsa:84061

    STRING: 9606.ENSP00000354649

    UniGene: Hs.323562



主站蜘蛛池模板: 国产精品欧美一区二区三区| 亚洲 国产 韩国 欧美 在线| 宅宅少妇无码| 欧美zozo另类特级| 亚洲欧美综合精品成人导航| 伊人99综合精品视频| 无码国产伦一区二区三区视频| 国产精品国产精品国产专区不卡| 麻豆精品导航| 亚洲和欧洲一码二码区别7777| 久久久久久九九精品久| 国产av无码专区亚洲版综合| 国产精品ⅴ无码大片在线看 | 精品国产v无码大片在线观看| 亚洲娇小与黑人巨大交| 非洲人与性动交ccoo| 日本一二免费不卡区| 2021最新国产精品网站| 中文字幕被公侵犯的漂亮人妻| 一边添奶一边添p好爽视频| 亚洲国内精品自在线影院| 欧美饥渴少妇xxxxx性| 亚洲 欧美 中文 在线 视频| 无码中文字幕日韩专区| 97超碰精品成人国产| 99视频有精品视频高清| 国产精品人妻一码二码| 亚洲免费观看在线视频| 精品噜噜噜噜久久久久久久久| 亚洲国产av无码综合原创国产| 202丰满熟女妇大| 成人欧美日韩一区二区三区| 国产精品无打码在线播放| 国产亚洲综合久久系列| 国产欧美一区二区精品性色| 成人亚洲a片v一区二区三区蜜臀| 中文字幕乱码免费专区| 巨人精品福利官方导航| 国产精品无码av天天爽播放器 | 亚洲国产精品美女久久久久| 熟女少妇精品一区二区|