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MAGEA9 Antibody

  • 中文名稱：
    MAGEA9兔多克隆抗體
  • 貨號(hào)：
    CSB-PA013335LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA013335LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA013335LA01HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MAGEA9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAGEA9
  • 別名：
    Cancer/testis antigen 1.9 antibody; Cancer/testis antigen family 1 member 9 antibody; CT1.9 antibody; MAGA9_HUMAN antibody; MAGE 9 antigen antibody; MAGE-9 antigen antibody; MAGE9 antibody; MAGEA9A antibody; MAGEA9B antibody; Melanoma antigen family A 9 antibody; Melanoma associated antigen 9 antibody; Melanoma-associated antigen 9 antibody; MGC8421 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Melanoma-associated antigen 9 protein (1-315AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，MAGEA9 Antibody (CSB-PA013335LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于MAGEA9 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA013335LB01HU MAGEA9 Antibody, HRP conjugated ELISA
    FITC CSB-PA013335LC01HU MAGEA9 Antibody, FITC conjugated
    Biotin CSB-PA013335LD01HU MAGEA9 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
  • 基因功能參考文獻(xiàn)：
    1. MAGE-A9 overexpression promoted cell proliferation, colony formation, migration, chemoresistance, and tumorigenicity in the context of EpCAM+ HCC cells, whereas MAGE-A9 knockdown significantly inhibited anchorage-dependent and spheroid colony formation and in vivo tumorigenicity. PMID: 29138811
    2. potential X-linked candidate for the CNV67-related spermatogenic failure phenotype PMID: 28339631
    3. High expression levels of MAGE-A9 are correlated with lung adenocarcinoma. PMID: 26717042
    4. The results showed that the high expression of MAGE-A9 protein in NSCLC tumor cells were commonly present in squamous cell carcinomas. It was also related to larger tumor diameter, lymph node metastasis and later stage grouping with TNM classification PMID: 25755744
    5. These data are the first to indicate that MAGE-A9 expression is a valuable prognostic biomarker for HCC and that high MAGE-A9 expression suggests unfavorable survival outcomes in HCC patients PMID: 25315972
    6. High expression of MAGE-A9 indicates unfavorable survival outcome in laryngeal squamous cell carcinoma patients. PMID: 25400753
    7. The data suggest that MAGE-A9 expression is correlated with malignant attributes of invasive ductal breast cancer PMID: 25445503
    8. MAGE-A9 and MAGE-A11 are tumor-specific antigens and not only DNA hypermethylation but also histone deacetylation is responsible for the mechanism underlying MAGE-A9 and MAGE-A11 gene silencing. PMID: 24316396
    9. May provide suitable targets for immunotherapy of renal cell carcinoma. PMID: 15900605
    10. Overexpression of MAGE-A9 is associated with bladder cancer. PMID: 19533752

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  • 組織特異性：
    Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 6807

    OMIM: 300342

    KEGG: hsa:4108

    STRING: 9606.ENSP00000298974

    UniGene: Hs.460974



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