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MAGEA2 Antibody

  • 中文名稱:
    MAGEA2兔多克隆抗體
  • 貨號:
    CSB-PA013327LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, Raji whole cell lysate
      All lanes: MAGEA2 antibody at 4.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 36 kDa
      Observed band size: 36 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAGEA2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MAGEA2
  • 別名:
    MAGEA2 antibody; MAGE2 antibody; MAGEA2A; antibody; MAGEA2B antibody; MAGE2 antibody; MAGEA2 antibody; Melanoma-associated antigen 2 antibody; Cancer/testis antigen 1.2 antibody; CT1.2 antibody; MAGE-2 antigen antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Melanoma-associated antigen 2 protein (1-104AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,MAGEA2 Antibody (CSB-PA013327LA01HU),的標記方式是Non-conjugated。對于MAGEA2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA013327LB01HU MAGEA2 Antibody, HRP conjugated ELISA
    FITC CSB-PA013327LC01HU MAGEA2 Antibody, FITC conjugated
    Biotin CSB-PA013327LD01HU MAGEA2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Negatively regulates acetylation and sumoylation of PML and represses PML-induced p53/TP53 acetylation and activation.
  • 亞細胞定位:
    Nucleus. Nucleus, PML body.
  • 組織特異性:
    Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
  • 數據庫鏈接:

    HGNC: 6800

    OMIM: 300173

    KEGG: hsa:266740

    STRING: 9606.ENSP00000359307

    UniGene: Hs.534597



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