在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. M6PR Antibody

M6PR Antibody

  • 中文名稱：
    M6PR兔多克隆抗體
  • 貨號：
    CSB-PA02625A0Rb
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA02625A0Rb at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA02625A0Rb at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA02625A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) M6PR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    M6PR
  • 別名：
    M6PR; MPR46; MPRD; Cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CD-MPR; 46 kDa mannose 6-phosphate receptor; MPR 46
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Cation-dependent mannose-6-phosphate receptor protein (1-277AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，M6PR Antibody (CSB-PA02625A0Rb)，的標記方式是Non-conjugated。對于M6PR Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA02625B0Rb M6PR Antibody, HRP conjugated ELISA
    FITC CSB-PA02625C0Rb M6PR Antibody, FITC conjugated
    Biotin CSB-PA02625D0Rb M6PR Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
  • 基因功能參考文獻：
    1. Most rotavirus strains require the cation-independent mannose-6-phosphate receptor, sortilin-1, and cathepsins to enter cells. PMID: 29275103
    2. In light of existing report suggesting critical role of Nef-GCC185 interaction reveals valuable mechanistic insights affecting specific protein transport pathway in docking of late endosome derived Rab9 bearing transport vesicle at TGN elucidating role of Nef during viral pathogenesis. PMID: 27105913
    3. Results suggest that Rab protein Rab29 is essential for the integrity of the trans-Golgi network (TGN) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR). PMID: 24788816
    4. These data indicate that clathrin is required for the function of AP-1- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane. PMID: 24407285
    5. Sortilin is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR is able to internalize circulating alpha-Gal A. PMID: 22768187
    6. Mannose receptor (MR) engagement by mesothelin GPI anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody PMID: 22163010
    7. mediates in vitro human immunodeficiency virus and sperm cell interaction PMID: 22015004
    8. sorting of the CD-MPR in late endosomes requires a distinct di-aromatic motif with only limited possibilities for variations PMID: 12697764
    9. All 5 MPRci-deficient lines resisted infection by cell-free, but not cell-associated, VZV, secreted lysosomal enzymes, and released infectious virions when infected by cell-associated VZV PMID: 15620351
    10. We conclude that the CI-MPR participates in lysosomal and granular targeting of serglycin and basic proteins such as lysozyme associated with the proteoglycan in hematopoietic cells. PMID: 17210618
    11. sortilin and mannose-6-phosphate receptors recycle to the TGN in SNX1-dependent carriers, which we named endosome-to-TGN transport carriers PMID: 18088323
    12. Missorting of cathepsin D in GARP-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes. PMID: 18367545
    13. Data demonstrate that Rab31 is required for transport of mannose 6-phosphate receptors from the trans-Golgi network to endosomes and for the Golgi/TGN organization. PMID: 19345684

    顯示更多

    收起更多

  • 亞細胞定位：
    Lysosome membrane; Single-pass type I membrane protein.
  • 數據庫鏈接：

    HGNC: 6752

    OMIM: 154540

    KEGG: hsa:4074

    STRING: 9606.ENSP00000000412

    UniGene: Hs.134084



主站蜘蛛池模板： 国产精品成人一区无码| 噜妇插内射精品| 日本妇人成熟免费| 久久久无码精品午夜| 国产精品香港三级国产av| 亚洲狠狠色成人综合网| 国产超碰人人做人人爽av动图| 久久亚洲日韩精品一区二区三区 | 国产色在线 | 国产| 老司机性色福利精品视频| 日韩99在线 | 中文| 日产精品久久久一区二区| 精品无码人妻一区二区三区不卡| 欧美性猛交xxxx富婆| 三级成年网站在线观看级爱网| 国产果冻豆传媒麻婆| 欲香欲色天天综合和网| 麻麻张开腿让我爽了一夜| 久久午夜电影网| 亚洲龙腾成小说人网| 在线观看国产丝袜控网站 | 国产成人精品精品日本亚洲| 精品人妻少妇一区二区| 青青草国产成人99久久| 女人被狂躁c到高潮喷水电影| 亚洲午夜无码久久久久小说| 婷婷色五月开心五月| 丝袜美腿一区二区三区| 欧美 国产 综合 欧美 视频| 久久成人国产精品免费| 国产美女被遭高潮免费网站| 亚洲精品成人av在线| 伊人激情av一区二区三区| 中文午夜乱理片无码| 久久久无码精品国产一区| 国产av无码专区亚汌a√| 无码人妻精一区二区三区| 精品国产乱码久久久久久夜深人妻 | 欧美牲交a欧美牲交aⅴ免费真| 手机在线看片| 国产ktv交换配乱婬视频|