在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LZTS1 Antibody

LZTS1 Antibody

  • 中文名稱：
    LZTS1兔多克隆抗體
  • 貨號：
    CSB-PA22699A0Rb
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA22699A0Rb diluted at 1:500 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA22699A0Rb at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LZTS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LZTS1
  • 別名：
    F37 antibody; F37/esophageal cancer related gene coding leucine zipper motif antibody; F37/esophageal cancer-related gene-coding leucine-zipper motif antibody; Fez1 antibody; Leucine zipper putative tumor suppressor 1 antibody; Lzts1 antibody; LZTS1_HUMAN antibody; Psdzip70 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine zipper putative tumor suppressor 1 protein (47-212AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，LZTS1 Antibody (CSB-PA22699A0Rb)，的標記方式是Non-conjugated。對于LZTS1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA22699B0Rb LZTS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA22699C0Rb LZTS1 Antibody, FITC conjugated
    Biotin CSB-PA22699D0Rb LZTS1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.
  • 基因功能參考文獻：
    1. missense variant in the LZTS1 gene was identified in two Ehlers-Danlos syndrome patients in an extended family. PMID: 26504261
    2. LZTS1 promoter was frequently methylated in IMPC samples. PMID: 25813822
    3. Compared with the normal hepatocyte cells, LZTS1 expression in hepatocellular carcinoma cells was significantly lower PMID: 26653561
    4. miR-135b expression inversely correlated with LZTS1 staining intensity and the Cutaneous Squamous Cell Carcinoma grade. PMID: 25938461
    5. Suggest that LZTS1 plays a potential tumor suppressor role in colorectal cancer progression and represents a valuable clinical prognostic marker of this disease. PMID: 25667121
    6. Lzts1 was significantly downregulated in breast cancer samples and its deregulation was associated with a higher incidence of tumor recurrence, and to a worse overall survival. PMID: 24448468
    7. miR-214 functions as an onco-miRNA in osteosarcoma, and its oncogenic effects are mediated chiefly through downregulation of LZTS1 PMID: 24802407
    8. Expression of miR-135b, LZTS1, LATS2 and nuclear TAZ predicts poor outcomes of non-small-cell lung cancer. PMID: 23695671
    9. Lower levels of leucine zipper putative tumor suppressor 1 correlated with high histologic grade, lymph node metastasis, and poor prognosis. PMID: 21419475
    10. variation in the germline sequence is associated with prostate cancer risk PMID: 12377406
    11. Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity is associated with oral squamous cell carcinomas PMID: 12851677
    12. Forced expression of LZTS1 in metastasizing uveal melanoma cells inhibited their motility and invasion, whereas depletion of LZTS1 increased their motility. PMID: 18559591
    13. Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis. PMID: 18686028
    14. The reduction or loss of FEZ1 protein could be an aid to the clinical management of patients affected by ovarian carcinoma. PMID: 19885841

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Esophageal cancer (ESCR)
  • 亞細胞定位：
    Cytoplasm. Cell membrane. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族：
    LZTS family
  • 組織特異性：
    Highly expressed in testis, prostate, spleen, thymus, ovary and brain. Detected at lower levels in heart, placenta, small intestine, colon, liver, kidney, skeletal muscle and pancreas. Not detectable in primary tumors from breast and prostate and in many
  • 數據庫鏈接：

    HGNC: 13861

    OMIM: 133239

    KEGG: hsa:11178

    STRING: 9606.ENSP00000265801

    UniGene: Hs.521432



主站蜘蛛池模板： 一边添奶一边添p好爽视频| 日本一二免费不卡区 | 国产精品无码2021在线观看 | 国产99视频精品免费专区| 人妻夜夜爽天天爽一区| 亚洲国产精品无码久久一区二区| 无码综合天天久久综合网色吧影院 | av无码中出一区二区三区| 国产成人高清精品亚洲| 四虎成人精品无码| 精品无码三级在线观看视频| 国产-第1页-浮力影院| 永久黄网站色视频免费无下载| 欧美性生交xxxxx无码久久久 | 国产成人无码一区二区在线播放 | 亚洲精品无码鲁网中文电影| 国产精品videossex国产高清| 精品国产av无码一区二区三区| 天天做天天爱天天综合网2021 | 丰满诱人的人妻3| 久久久久久久岛国免费观看| 欧美精欧美乱码一二三四区| 老头边吃奶边弄进去呻吟| 亚洲国产成人乱码| 99久久久无码国产精品古装 | 亚洲国产精品无码一区二区三区 | 国产l精品国产亚洲区| 国产香蕉97碰碰久久人人| 国产人妻精品一区二区三区| 国产精品无码专区久久久| 亚洲精品久久国产精品浴池| 中文字幕精品av乱码在线| 人人妻人人澡人人爽不卡视频| 日本熟妇色xxxxx日本免费看| 久久综合九色综合97伊人| 欧美黑人巨大videos极品| 人禽伦免费交视频播放| 日本十八禁视频无遮挡| 久久香蕉国产线看观看手机| 国产超碰人人做人人爱| 国产天堂亚洲国产碰碰|