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  4. LYRM1 Antibody, FITC conjugated

LYRM1 Antibody, FITC conjugated

  • 中文名稱：
    LYRM1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA013272LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) LYRM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LYRM1
  • 別名：
    1110065L10Rik antibody; 2310004B22Rik antibody; 4930404J24Rik antibody; A211C6.1 antibody; LYR motif containing 1 antibody; LYR motif containing protein 1 antibody; LYR motif-containing protein 1 antibody; LYRM 1 antibody; lyrm1 antibody; LYRM1_HUMAN antibody; OTTHUMP00000162292 antibody; OTTMUSP00000031126 antibody; OTTMUSP00000031127 antibody; OTTMUSP00000031128 antibody; OTTMUSP00000031129 antibody; RGD1563498 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human LYR motif-containing protein 1 protein (1-122AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May promote cell proliferation and inhibition of apoptosis of preadipocytes.
  • 基因功能參考文獻(xiàn)：
    1. alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. PMID: 22820890
    2. overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin resistance PMID: 20826099
    3. Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development. PMID: 20938407
    4. By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis PMID: 19022914
  • 相關(guān)疾病：
    When overexpressed, may be involved in obesity-associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Complex I LYR family
  • 組織特異性：
    High levels in adipose tissue.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25074

    OMIM: 614709

    KEGG: hsa:57149

    STRING: 9606.ENSP00000219168

    UniGene: Hs.745012



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