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  4. LYPLAL1 Antibody

LYPLAL1 Antibody

  • 中文名稱：
    LYPLAL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA013271GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    LYPLAL1
  • 別名：
    BC027340 antibody; FLJ99730 antibody; KIAA1238 antibody; LYPL1_HUMAN antibody; LYPLAL1 antibody; Lysophospholipase like 1 antibody; Lysophospholipase-like protein 1 antibody; MGC28394 antibody; OTTHUMP00000035229 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Human LYPLAL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.
  • 基因功能參考文獻(xiàn)：
    1. Novel LYPLAL1 SNP rs2605100 is associated with childhood hypertension adjusted by obesity. PMID: 28645872
    2. The LYPLAL1 genotype is associated with differences in eating behavior and loss of extensive body weight following Roux-en-Y gastric bypass (RYGB) surgery. Genotyping and the use of eating behavior-related questionnaires may help to estimate the RYGB-associated therapy success. PMID: 27181159
    3. Data provide evidence that variants of MC4R and LYPLAL1 modulate body fat distribution with sexual dimorphism in a Chinese population. PMID: 26848030
    4. Our results suggest that LYPLAL1 rs4846567 and NISCH rs6784615 may influence fat distribution in the Japanese population. PMID: 23221025
    5. genetic association studies in Danish population: Quantitative metabolic phenotypes in obesity are associated with SNP in various genes: LYPLAL1 (rs4846567) is associated with waist-hip ratio and insulin sensitivity in women. PMID: 21953277
    6. Gene-treatment interactions were observed for short-term weight loss. (LYPLAL1 rs2605100, Plifestyle*SNP = 0.032) PMID: 22179955
    7. LYPLAL1 exhibits neither phospholipase nor triacylglycerol lipase activity, but rather accepts short-chain substrates PMID: 22052940
    8. central obesity-associated variants in LYPLAL1, NRXN3, MSRA, and TFAP2B PMID: 21674055
    9. TFAP2B, LYPLAL1 and MSRA are associated with adiposity and fat distribution. PMID: 19557161

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  • 亞細(xì)胞定位：
    [Isoform 1]: Cytoplasm, cytosol.; [Isoform 2]: Cytoplasm, cytosol.
  • 蛋白家族：
    AB hydrolase superfamily, AB hydrolase 2 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20440

    OMIM: 616548

    KEGG: hsa:127018

    STRING: 9606.ENSP00000355895

    UniGene: Hs.657617



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