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  4. LRRC4C Antibody

LRRC4C Antibody

  • 中文名稱：
    LRRC4C兔多克隆抗體
  • 貨號：
    CSB-PA888027LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA888027LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA888027LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA888027LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LRRC4C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LRRC4C
  • 別名：
    LRRC4C; KIAA1580; NGL1; UNQ292/PRO331; Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; NGL-1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat-containing protein 4C protein (201-500AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，LRRC4C Antibody (CSB-PA888027LA01HU)，的標記方式是Non-conjugated。對于LRRC4C Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA888027LB01HU LRRC4C Antibody, HRP conjugated ELISA
    FITC CSB-PA888027LC01HU LRRC4C Antibody, FITC conjugated
    Biotin CSB-PA888027LD01HU LRRC4C Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May promote neurite outgrowth of developing thalamic neurons.
  • 基因功能參考文獻：
    1. These data suggest that the proband's autism may be due to the inheritance of disruptions in both DPP6 and LRRC4C, and may highlight the importance of the netrin G family and potassium channel interacting molecules in neurodevelopmental disorders. PMID: 27759917
    2. Interaction between the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses. PMID: 23986473
    3. netrin-G1 functions as an important component of the NGL-1 receptor to promote TCA outgrowth and that membrane-bound netrins can participate in receiving axonal signaling pathways. PMID: 14595443
    4. NGL-1 is most abundant in the striatum and the cerebral cortex--the intermediate and final targets, of thalamocortical axons; surface-bound NGL-1 stimulates, but soluble NGL-1 disrupts, the growth of embryonic thalamic axons. PMID: 14595443
  • 亞細胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show v
  • 數據庫鏈接：

    HGNC: 29317

    OMIM: 608817

    KEGG: hsa:57689

    STRING: 9606.ENSP00000278198

    UniGene: Hs.745123



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