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  4. LRRC3B Antibody, Biotin conjugated

LRRC3B Antibody, Biotin conjugated

  • 中文名稱：
    LRRC3B兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA857000LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LRRC3B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LRRC3B
  • 別名：
    LRRC3B; LRP15; UNQ195/PRO221; Leucine-rich repeat-containing protein 3B; Leucine-rich repeat protein 15
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeat-containing protein 3B protein (34-204AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. The expression of LRRC3B is downregulated in non-small cell lung cancer compared with normal epithelial cells. PMID: 27118644
    2. LRRC3B may serve as an important tumor suppressor in non-small-cell lung cancer PMID: 26276358
    3. LRRC3B gene expression and promoter hypermethylation in breast carcinomas PMID: 24839112
    4. Data suggest that LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene. PMID: 22321817
    5. The LRRC3B gene promoter was methylated in 43% of clear cell renal carcinoma samples. PMID: 22101383
    6. The expression of LRP15 is controlled by methylation in its promoter in HeLa cells, and LRP15 confers resistance to ultraviolet rays damage and accelerates the DNA repair rate. PMID: 18377727
    7. suggest that LRRC3B is a putative tumor suppressor gene that is silenced in gastric cancers by epigenetic mechanisms and that LRRC3B silencing in cancer may play an important role in tumor escape from immune surveillance PMID: 18757430
    8. LRRC3B may be a novel methylation-sensitive tumor suppressor gene in CRC. LRRC3B methylation has significant tumor specificity and may be a biomarker of CRC. PMID: 18815942

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  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    LRRC3 family
  • 數據庫鏈接：

    HGNC: 28105

    KEGG: hsa:116135

    STRING: 9606.ENSP00000379880

    UniGene: Hs.517868



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