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LRR1 Antibody

  • 中文名稱:
    LRR1兔多克隆抗體
  • 貨號:
    CSB-PA018486GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    LRR1
  • 別名:
    4 1BB mediated signaling molecule antibody; 4 1BBlrr antibody; 4-1BB-mediated-signaling molecule antibody; 4-1BBlrr antibody; Cyclophilin like 5 antibody; Leucine-rich repeat protein 1 antibody; LLR1_HUMAN antibody; LRR 1 antibody; LRR repeat protein 1 antibody; LRR-1 antibody; LRR-repeat protein 1 antibody; LRR1 antibody; MGC20689 antibody; peptidylprolyl isomerase (cyclophilin) like 5 antibody; Peptidylprolyl isomerase like 5 antibody; Peptidylprolyl isomerase-like 5 antibody; PPIL5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PPIL5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 基因功能參考文獻:
    1. Results identify the CRL2(LRR-1) ubiquitin ligase as a conserved regulator of Cip/Kip CKIs that promotes the degradation of C. elegans CKI-1 and human p21. PMID: 21074724
  • 組織特異性:
    Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
  • 數據庫鏈接:

    HGNC: 19742

    OMIM: 609193

    KEGG: hsa:122769

    STRING: 9606.ENSP00000298288

    UniGene: Hs.451090



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