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  4. LRIG2 Antibody, Biotin conjugated

LRIG2 Antibody, Biotin conjugated

  • 中文名稱：
    LRIG2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA013085LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) LRIG2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LRIG2
  • 別名：
    KIAA0806 antibody; Leucine rich repeats and immunoglobulin like domains 2 antibody; Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody; LIG-2 antibody; LIG2 antibody; LRIG2 antibody; LRIG2_HUMAN antibody; UFS2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 protein (833-932AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
    2. Role of LRIG2 in cancer [review] PMID: 27628597
    3. LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
    4. A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
    5. Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
    6. LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
    7. LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
    8. LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
    9. This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012

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  • 相關疾病：
    Urofacial syndrome 2 (UFS2)
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 組織特異性：
    Detected in all tissues analyzed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20889

    OMIM: 608869

    KEGG: hsa:9860

    STRING: 9606.ENSP00000355396

    UniGene: Hs.448972



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