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  4. LPO Antibody, HRP conjugated

LPO Antibody, HRP conjugated

  • 中文名稱：
    LPO兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA013066LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LPO Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LPO
  • 別名：
    LPO antibody; SAPX antibody; Lactoperoxidase antibody; LPO antibody; EC 1.11.1.7 antibody; Salivary peroxidase antibody; SPO antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Lactoperoxidase protein (81-190AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection.
  • 基因功能參考文獻：
    1. The crystal structure of the complex of LPO with MZY showed that MZY bound to LPO in the substrate-binding site on the distal heme side. MZY was oriented in the substrate-binding site in such a way that the sulfur atom is at a distance of 2.58 A from the heme iron PMID: 28653416
    2. LPO mRNA was undetectable in the gastric mucosa. PMID: 27048452
    3. Oral peroxidase activity as a marker of chronic alcohol abuse may help in the diagnosis of alcoholism. PMID: 23042278
    4. establish urate as a likely physiological substrate for LPO that will influence host defense and give rise to reactive electrophilic metabolites PMID: 24928513
    5. High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase. PMID: 24974109
    6. a functional LPO system exists in human airways and may contribute to airway host defense against infection PMID: 12626341
    7. lactoperoxidase may play an important role in the metabolic events associated with Parkinson's disease PMID: 15384204
    8. Analysis of the role of thiocyanate (SCN-), in modulating the catalytic activity of myeloperoxidase (MPO) and other members of the lactoperoxidase (LPO) and eosinophil peroxidase (EPO) PMID: 15894800
    9. Splice variants may contribute to LPO molecular heterogeneity and its regulation by intracellular compartmental localization in respiratory epithelium. PMID: 19059195

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Peroxidase family, XPO subfamily
  • 組織特異性：
    Mammary gland; milk and salivary gland. Found in bronchial submucosal glands.
  • 數據庫鏈接：

    HGNC: 6678

    OMIM: 150205

    KEGG: hsa:4025

    STRING: 9606.ENSP00000262290

    UniGene: Hs.234742



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