在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LPIN2 Antibody

  • 中文名稱:
    LPIN2兔多克隆抗體
  • 貨號(hào):
    CSB-PA013063GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    LPIN2
  • 別名:
    KIAA0249 antibody; Lipin-2 antibody; Lipin2 antibody; LPIN 2 antibody; LPIN2 antibody; LPIN2_HUMAN antibody; OTTHUMP00000162242 antibody; Phosphatidate phosphatase LPIN2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Human LPIN2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
  • 基因功能參考文獻(xiàn):
    1. Structural variants unique to the malignant cell line inactivated: LPIN2, a phosphatidic acid phosphatase and a co-factor of PGC1a that is important for lipid metabolism and for suppressing autoinflammation. PMID: 23792589
    2. We describe two brothers with Majeed syndrome, homozygous novel 2-base pair deletion in LPIN2 (c.1312_1313delCT; p.Leu438fs+16X) PMID: 23087183
    3. LPIN1-related myolysis constitutes a major cause of early-onset rhabdomyolysis and occasionally in adults. Heterozygous LPIN1 mutations may cause mild muscular symptoms. No major defects of LPIN2 or LPIN3 genes were associated with muscle manifestations. PMID: 22481384
    4. role of lipin-2 in the proinflammatory action of saturated fatty acids in murine and human macrophages PMID: 22334674
    5. Data revealed that lipin 1 formed stable homo-oligomers with itself and hetero-oligomers with lipin 2/3. PMID: 20735359
    6. LPIN2 gene was excluded as a candidate for myopia 2 (MYP2), but the SNPs detected in this study will aid in future mapping and association studies involving this gene. PMID: 15862761
    7. We conclude that homozygous mutations in LPIN2 result in Majeed syndrome. Understanding the aberrant immune response in this condition will shed light on the aetiology of other inflammatory disorders of multifactorial aetiology PMID: 15994876
    8. A single nucleotide polymorphism of the LPIN2 gene is associated with type 2 diabetes and fat distribution. PMID: 17804763
    9. distinct and non-redundant functions of lipin 1 and 2 regulate lipid production during the cell cycle and adipocyte differentiation PMID: 18694939
    10. lipin 2 plays an important role as a hepatic PAP-1 enzyme. PMID: 19136718
    11. A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. PMID: 19717560

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Majeed syndrome (MJDS)
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane.
  • 蛋白家族:
    Lipin family
  • 組織特異性:
    Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14450

    OMIM: 605519

    KEGG: hsa:9663

    STRING: 9606.ENSP00000261596

    UniGene: Hs.132342



主站蜘蛛池模板: 国产乱子伦精品无码专区| 欧美 日韩 国产 另类 图片区| 四虎永久在线精品免费一区二区| 在线a亚洲v天堂网2018| 久久精品人人做人人爽老司机| 国产经典三级av在线播放| 噜噜高清欧美内射短视频| 欧美牲交a欧美牲交aⅴ免费真 | 亚洲成av人在线观看网站| 天堂在线最新版资源www中文| 人妻少妇av无码一区二区| 色综久久综合桃花网国产精品| 久草热久草热线频97精品| 真实国产老熟女无套中出| 成在人线av无码免费看| 日射精情感性色视频| 无码国模国产在线观看| 中国女人内谢69xxxx| 综合久久国产九一剧情麻豆 | 色偷偷一区二区无码视频| 51精品国产人成在线观看| 成人看片黄a免费看在线| 久久人妻无码aⅴ毛片a片app| 本道久久综合无码中文字幕| 大陆极品少妇内射aaaaa| 日韩人妻熟女中文字幕a美景之屋| 真人做人60分钟啪啪免费看| 波多野成人无码精品电影| 6080yyy午夜理论片中无码| 中文无码精品a∨在线观看不卡 | 国产亚洲综合区成人国产| 尤物蜜芽国产成人精品区| 午夜精品久久久久久久喷水| 国产极品美女高潮抽搐免费网站| 国产美女亚洲精品久久久| 久久香蕉国产线看观看猫咪av| 人妻熟女αⅴ一区二区三区| 国产精品人妻久久毛片高清无卡| 亚洲综合久久成人a片| 可以直接看的无码av| 久久国产成人免费网站777|