在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LPAR5 Antibody, Biotin conjugated

  • 中文名稱:
    LPAR5兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA013051OD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LPAR5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    LPAR5; GPR92; GPR93; Lysophosphatidic acid receptor 5; LPA receptor 5; LPA-5; G-protein coupled receptor 92; G-protein coupled receptor 93
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Lysophosphatidic acid receptor 5 protein (310-326AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
  • 基因功能參考文獻:
    1. It signaling may play a key role in the mechanisms underlying neuropathic pain following demyelination in the brain. PMID: 29409686
    2. These results suggest that the cell motile activity is regulated through the induction of LPA5 by phorbol ester and anticancer drug treatments in A375cells. PMID: 29309788
    3. These results suggest that the diverse roles of LPA4, LPA5 and LPA6 are involved in the activation of tumor progression in pancreatic cancer cells. PMID: 25849892
    4. Down-regulation of LPA receptor 5 contributes to aberrant LPA signalling in EBV-associated nasopharyngeal carcinoma. PMID: 25294670
    5. MMP-2 and MMP-9 were found in HT1080L5 cells, in comparison with control cells. These results suggest that LPA signaling via LPA5 negatively regulates the cell motile and invasive activities of human sarcoma cells. PMID: 24676544
    6. These results suggest that LPA5 may act as a negative regulator of cellular responses in mouse fibroblast 3T3 cells, similar to the case for LPA1. PMID: 24632199
    7. It was shown that lysophosphatidic acid 5 receptor transactivated the epidermal growth factor receptor and that inhibition of epidermal growth factor receptor blocked lysophosphatidic acid 5 receptor-dependent activation of NHE3. PMID: 21832242
    8. LPA5 is a bona fide LPA receptor on human mast cells responsible for the majority of LPA induced MIP-1beta release. PMID: 21464938
    9. LPA4 and LPA5 receptors induce osteoblastic differentiation of human mesenchymal stem cells PMID: 20069565
    10. Data show that CLL cells express LPA receptors LPA(1-5) and VEGF receptors, and the plasma levels of VEGF are elevated in CLL patients. PMID: 19860625
    11. GPR92 is proposed as a fifth LPA receptor, LPA5, which likely has distinct physiological functions in view of its expression pattern. PMID: 16774927
    12. FPP and NAG play a role in the sensory nervous system through activation of GPR92 PMID: 18499677
    13. Four residues involved in ligand recognition in LPA(5) were identified as follows: R2.60N mutant abolished receptor activation, whereas H4.64E, R6.62A, and R7.32A greatly reduced receptor activation. PMID: 19366702

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.
  • 數據庫鏈接:

    HGNC: 13307

    OMIM: 606926

    KEGG: hsa:57121

    STRING: 9606.ENSP00000327875

    UniGene: Hs.155538



主站蜘蛛池模板: 免费国产裸体美女视频全黄| 亚洲男人综合久久综合天堂| 少妇高潮惨叫久久久久电影| av电影在线观看| 亚洲精品一区二区三区在线| 婷婷五月综合激情中文字幕| 国产亚洲999精品aa片在线爽| 国产欧美日韩视频一区二区三区| 久久99精品国产99久久6不卡| 免费又黄又硬又爽大片| 激情毛片无码专区| 亚洲精品久久久久高潮| 亚洲精品高清国产一久久| 中文字幕人妻互换av久久| 日本护士╳╳╳hd少妇| 欧美极p品少妇的xxxxx| 日日碰狠狠添天天爽五月婷| 人妻饥渴偷公乱中文字幕| 激情综合色综合久久综合| 动漫精品无码h在线观看| 亚洲精品国产av成拍色拍婷婷| 久久国语露脸国产精品电影| 欧美亅性猛交内射| 1313午夜精品理论片| 无码办公室丝袜ol中文字幕| 97午夜理论片在线影院| 国产亚洲香蕉线播放αv38| 超清无码波多野吉衣中文| 亚洲欧美另类久久久精品| 国产成人亚洲综合精品| 久9视频这里只有精品试看| 色狠狠色狠狠综合天天| 亚洲精品国精品久久99热| 亚洲欧美人高清精品a∨| 国产精品无码一本二本三本色 | 国产精品岛国久久久久| 少女高清影视在线观看动漫| 性饥渴少妇av无码毛片| 免费体验区试看120秒| 久久超碰97人人做人人爱| 欧美特大特白屁股ass|