在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LPAR5 Antibody, Biotin conjugated

  • 中文名稱:
    LPAR5兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA013051OD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LPAR5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    LPAR5; GPR92; GPR93; Lysophosphatidic acid receptor 5; LPA receptor 5; LPA-5; G-protein coupled receptor 92; G-protein coupled receptor 93
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Lysophosphatidic acid receptor 5 protein (310-326AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
  • 基因功能參考文獻:
    1. It signaling may play a key role in the mechanisms underlying neuropathic pain following demyelination in the brain. PMID: 29409686
    2. These results suggest that the cell motile activity is regulated through the induction of LPA5 by phorbol ester and anticancer drug treatments in A375cells. PMID: 29309788
    3. These results suggest that the diverse roles of LPA4, LPA5 and LPA6 are involved in the activation of tumor progression in pancreatic cancer cells. PMID: 25849892
    4. Down-regulation of LPA receptor 5 contributes to aberrant LPA signalling in EBV-associated nasopharyngeal carcinoma. PMID: 25294670
    5. MMP-2 and MMP-9 were found in HT1080L5 cells, in comparison with control cells. These results suggest that LPA signaling via LPA5 negatively regulates the cell motile and invasive activities of human sarcoma cells. PMID: 24676544
    6. These results suggest that LPA5 may act as a negative regulator of cellular responses in mouse fibroblast 3T3 cells, similar to the case for LPA1. PMID: 24632199
    7. It was shown that lysophosphatidic acid 5 receptor transactivated the epidermal growth factor receptor and that inhibition of epidermal growth factor receptor blocked lysophosphatidic acid 5 receptor-dependent activation of NHE3. PMID: 21832242
    8. LPA5 is a bona fide LPA receptor on human mast cells responsible for the majority of LPA induced MIP-1beta release. PMID: 21464938
    9. LPA4 and LPA5 receptors induce osteoblastic differentiation of human mesenchymal stem cells PMID: 20069565
    10. Data show that CLL cells express LPA receptors LPA(1-5) and VEGF receptors, and the plasma levels of VEGF are elevated in CLL patients. PMID: 19860625
    11. GPR92 is proposed as a fifth LPA receptor, LPA5, which likely has distinct physiological functions in view of its expression pattern. PMID: 16774927
    12. FPP and NAG play a role in the sensory nervous system through activation of GPR92 PMID: 18499677
    13. Four residues involved in ligand recognition in LPA(5) were identified as follows: R2.60N mutant abolished receptor activation, whereas H4.64E, R6.62A, and R7.32A greatly reduced receptor activation. PMID: 19366702

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.
  • 數據庫鏈接:

    HGNC: 13307

    OMIM: 606926

    KEGG: hsa:57121

    STRING: 9606.ENSP00000327875

    UniGene: Hs.155538



主站蜘蛛池模板: 黄网站成人片免费视频| 韩国乱码伦视频免费| 色五月五月丁香亚洲综合网| 2018天天躁夜夜躁狠狠躁| 亚洲精品无码av人在线观看国产 | 日本午夜看x费免| 狠日狠干日日射| 中文无码av一区二区三区| 最近免费中文字幕中文高清百度| 欧美嫩交一区二区三区| 人人狠狠综合久久亚洲爱咲| 人妻少妇中文字幕乱码| 国产手机在线国内精品| 天堂在线www资源在线| 亚洲欧美黑人深喉猛交群| 老熟女五十路乱子交尾中出一区| 国语精品福利自产拍在线观看| 人妻无码vs中文字幕久久av爆| 欧美日韩精品一区二区在线观看| 人妻体体内射精一区二区| 在线日产精品一区| 久久久肥妇熟女ⅹxxx毛片| 真实国产乱啪福利露脸| 少妇人妻精品一区二区| 欧美日韩在手机线旡码可下载 | 中国做爰国产精品视频| 国产精品区av| 中文字幕亚洲乱码熟女在线| 国产成人精品一区二区三区免费看| 中国猛少妇色xxxxx| 国产女人高潮叫床视频| 成人无码视频在线观看大全| 久久无码精品一一区二区三区 | 一区二区视频| 久久婷婷久久一区二区三区| 国产精品aⅴ视频在线播放| 大白肥妇bbvbbw高潮| 99精品国产兔费观看久久99| 亚洲中文字幕在线精品2021| 精品一区二区三区四区五区六区 | 99久久精品免费看国产一区二区三区|