在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LOXL4 Antibody

  • 中文名稱:
    LOXL4兔多克隆抗體
  • 貨號:
    CSB-PA567337
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA567337(LOXL4 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    LOXL4
  • 別名:
    4833426I20Rik antibody; FLJ21889 antibody; LOX L4 antibody; LOXC antibody; LOXL 4 antibody; LOXL4 antibody; LOXL4_HUMAN antibody; Lysyl oxidase homolog 4 antibody; Lysyl oxidase like 4 antibody; Lysyl oxidase like protein 4 antibody; Lysyl oxidase related C antibody; Lysyl oxidase related protein C antibody; Lysyl oxidase-like protein 4 antibody; Lysyl oxidase-related protein C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human LOXL4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May modulate the formation of a collagenous extracellular matrix.
  • 基因功能參考文獻:
    1. study describes for the first time a direct link between a retinoic-induced gene and protein, LOXL4, and its general clinical pro-healing properties in ECM dynamics PMID: 27597564
    2. Although expression of LOXL4 is not statistically associated with neck metastases, we showed that LOXL4 expression significantly increased in laryngeal cancer. PMID: 26138381
    3. In hepatocellular carcinoma, low LOXL4 expression was associated with lower overall survival rates and higher cumulative recurrence rates. PMID: 26097573
    4. These results provide a set of the essential genes in this newly identified miR-193a-3p/LOXL4/Oxidative Stress axis. PMID: 25311867
    5. High Lysyl oxidase-like 4 promotes proliferation and metastasis of gastric cancer via FAK/Src pathway. PMID: 25216702
    6. data suggest that abnormal expression of LOXL4 of KCOT may enhance angiogenesis in KCOT, which may help to promote the locally aggressive biological behavior of KCOT. PMID: 24357854
    7. TGF-beta1 induced injured MCL to express more LOXs than injured ACL (up to 1.85-fold in LOX, 2.21-fold in LOXL-1, 1.71-fold in LOXL-2, 2.52-fold in LOXL-3 and 3.32-fold in LOXL-4). PMID: 23357697
    8. Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer. PMID: 22806361
    9. The human lysyl oxidase-like 4 gene does not confer increased genotypic risk for adolescent idiopathic scoliosis. PMID: 21740577
    10. SNPs in the lysyl oxidase-like protein 4 and complement component 3 genes are associated with increased risk for endometriosis and endometriosis-associated infertility in a Puerto Rican population. PMID: 21733505
    11. Overexpression of the lysyl oxidase-like 4 gene is associated with metastatic head/neck carcinoma. PMID: 21115907
    12. The data presented in this work might emphasize the involvement of LOXL4 in molecular processes of the genesis or progression of head and neck carcinomas. PMID: 12894545
    13. LOXL4, with the four scavenger receptor cysteine rich domains, may also function as an active amine oxidase PMID: 14551188
    14. Up-regulation of lysyl oxidase mRNA and protein expression is associated with oral squamous cell carcinoma PMID: 17671119
    15. LOXL4-DC stimulated T cells produce higher IFN-gamma secretion compared to unstimulated T cells and T cells stimulated with untransfected DCs, in the presence of the pan-DR-epitope (PADRE) PMID: 18202753
    16. These results suggest that LOXL4 may function as a negative feedback regulator of TGF-beta1 in cell invasion by inhibiting the metabolism of extracellular matrix (ECM) components. PMID: 18586005
    17. Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells. PMID: 18949373
    18. In breast carcinoma, LOXL4 was expressed only in the effusion samples. In malignant mesothelioma, LOXL4 and its splice variants were expressed at all sites. PMID: 19015874

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space.
  • 蛋白家族:
    Lysyl oxidase family
  • 組織特異性:
    Expressed in many tissues, the highest levels among the tissues studied being in the skeletal muscle, testis and pancreas. Expressed in cartilage.
  • 數據庫鏈接:

    HGNC: 17171

    OMIM: 607318

    KEGG: hsa:84171

    STRING: 9606.ENSP00000260702

    UniGene: Hs.306814



主站蜘蛛池模板: 一本大道久久东京热av| 国产精品日本亚洲欧美| 青椒国产97在线熟女| 国产 | 欧洲野花视频天堂视频p| 4444亚洲人成无码网在线观看| 国产特级毛片aaaaaaa高清| 99国产精品久久久久久久成人| 青青草国产精品一区二区| 国产国产成人久久精品| 女女女女女裸体开bbb| 熟妇人妻中文字幕| 青娱乐极品视觉盛宴国产视频| 亚洲欧美日韩国产综合在线一区| 国产内射xxxxx在线| 一区二区和激情视频| 女人高潮内射99精品| 成人视频在线观看| 亚洲色欲天天天堂色欲网| 色天使久久综合给合久久97色 | 720lu国产刺激无码| 国产新婚夫妇叫床声不断| 极品白嫩的小少妇| 色综合久久久久无码专区| 人妻一区二区三区高清av专区 | 精品夜夜澡人妻无码av蜜桃| 国产国语毛片在线看国产| 国产按头口爆吞精在线视频| 天堂无码人妻精品av一区 | 免费观看全黄做爰的视频| 无套熟女av呻吟在线观看| 99热网址最新获取域名| 韩国精品视频一区二区在线播放| 亚洲a∨无码无在线观看| 国产高清视频一区三区| 狠狠色狠狠色五月激情| 男女啪啪高清无遮挡免费| 久久精品国产免费观看| 欧美 国产 日产 韩国 在线| 韩国午夜福利片在线| 国产又黄又大又粗视频| 日韩成人极品在线内射3p蜜臀|